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非回波平面扩散加权磁共振成像(周期性旋转重叠平行线增强重建序列)与回波平面成像用于检测中耳胆脂瘤的比较

Non echo planar, diffusion-weighted magnetic resonance imaging (periodically rotated overlapping parallel lines with enhanced reconstruction sequence) compared with echo planar imaging for the detection of middle-ear cholesteatoma.

作者信息

Kasbekar A V, Scoffings D J, Kenway B, Cross J, Donnelly N, Lloyd S W K, Moffat D, Axon P R

机构信息

Department of Otolaryngology, Cambridge University Hospitals NHS Trust, UK.

出版信息

J Laryngol Otol. 2011 Apr;125(4):376-80. doi: 10.1017/S0022215110002197. Epub 2010 Nov 29.

Abstract

OBJECTIVES

We evaluated use of the periodically rotated overlapping parallel lines with enhanced reconstruction diffusion-weighted imaging sequence, compared with conventional echo planar magnetic resonance imaging, in the detection of middle-ear cholesteatoma.

MATERIAL AND METHODS

Sixteen patients awaiting second-stage combined approach tympanoplasty and three patients awaiting first-stage combined approach tympanoplasty underwent magnetic resonance imaging with both (1) the periodically rotated overlapping parallel lines with enhanced reconstruction sequence (i.e. non echo planar imaging) and (2) the array spatial sensitivity encoding technique sequence (i.e. echo planar imaging). Two neuroradiologists independently evaluated the images produced by both sequences. Radiology findings were correlated with surgical findings.

RESULTS AND ANALYSIS

Seven cholesteatomas were found at surgery. Neither of the assessed imaging sequences were able to detect cholesteatoma of less than 4 mm. Rates for sensitivity, specificity, and positive and negative predictive values are presented.

CONCLUSION

Decisions on whether or not to operate for cholesteatoma cannot be made based on the two imaging sequences assessed, as evaluated in this study. Other contributing factors are discussed, such as the radiological learning curve and technical limitations of the magnetic resonance imaging equipment.

摘要

目的

我们评估了与传统回波平面磁共振成像相比,周期性旋转重叠平行线增强重建扩散加权成像序列在检测中耳胆脂瘤中的应用。

材料与方法

16例等待二期联合进路鼓室成形术的患者和3例等待一期联合进路鼓室成形术的患者接受了磁共振成像检查,检查时分别使用(1)周期性旋转重叠平行线增强重建序列(即非回波平面成像)和(2)阵列空间灵敏度编码技术序列(即回波平面成像)。两名神经放射科医生独立评估了两种序列产生的图像。放射学检查结果与手术结果相关。

结果与分析

手术中发现7例胆脂瘤。两种评估的成像序列均无法检测到小于4毫米的胆脂瘤。给出了灵敏度、特异性以及阳性和阴性预测值。

结论

如本研究评估所示,不能基于所评估的两种成像序列来决定是否对胆脂瘤进行手术。还讨论了其他相关因素,如放射学学习曲线和磁共振成像设备的技术局限性。

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