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5-氟尿嘧啶的心脏毒性:一项批判性综述。

5-Fluorouracil cardiotoxicity: a critical review.

作者信息

Gradishar W J, Vokes E E

机构信息

Department of Medicine, Pritzker School of Medicine, University of Chicago.

出版信息

Ann Oncol. 1990 Nov;1(6):409-14. doi: 10.1093/oxfordjournals.annonc.a057793.

DOI:10.1093/oxfordjournals.annonc.a057793
PMID:2083185
Abstract

5-Fluorouracil is a commonly administered chemotherapy agent that has infrequently been associated with cardiotoxicity. This review highlights the clinical features of this syndrome as described in reports from the medical literature. Clinical and laboratory evidence supporting proposed underlying mechanisms are reviewed.

摘要

5-氟尿嘧啶是一种常用的化疗药物,很少与心脏毒性相关。本综述重点介绍了医学文献报道中该综合征的临床特征。对支持所提出潜在机制的临床和实验室证据进行了综述。

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