Otokunefor T V, Datubo-Brown D D
Department of Microbiology, University of Port Harcourt.
West Afr J Med. 1990 Oct-Dec;9(4):285-90.
Seventy nine swab specimens obtained from various categories of wounds suspected to be infected on clinical grounds were cultured for the presence of aerobic bacteria and their pattern of antibiotic sensitivity determined. The twin genera of Staphylococcus and Pseudomonas contributed equally to burn infections while Staphylococcus species were clearly predominant in surgical wound infections. Pseudomonas species were more common in ulcers which were also characterised by a higher incidence of Escherichia coli and multiple microbial infections. The isolates were generally very resistant to the test antibiotics and showed very little sensitivity to commonly used antibiotics such as compound sulphonamides, ampicillin, cotrimoxazole and tetracycline. However, in vitro sensitivity to colistin and gentamycin was considered moderate. The need for judicious choice of antibiotics in the treatment of bacterial infections is stressed.
对79份从临床上怀疑感染的各类伤口获取的拭子标本进行培养,以检测需氧菌的存在并确定其抗生素敏感性模式。葡萄球菌属和假单胞菌属在烧伤感染中所占比例相同,而葡萄球菌在手术伤口感染中明显占主导地位。假单胞菌在溃疡中更为常见,溃疡还具有大肠杆菌发病率较高和多重微生物感染的特点。分离出的菌株通常对测试抗生素具有很强的耐药性,对复方磺胺类、氨苄青霉素、复方新诺明和四环素等常用抗生素的敏感性很低。然而,体外试验表明,这些菌株对黏菌素和庆大霉素的敏感性中等。强调了在治疗细菌感染时明智选择抗生素的必要性。