Emele F E, Izomoh M I, Alufohai E
Department of Medical Microbiology, College of Medicine, Faculty of Natural Sciences, Edo State University, Ekpoma.
West Afr J Med. 1999 Apr-Jun;18(2):97-100.
Bacteria associated with wound infection in Ekpoma, Nigeria, and their antimicrobial susceptibility profile was investigated by standard microbiological methods, using hospital as well as non-hospital patients. Of 40 patients seen, 25 (62.5%) were males, while the rest were females. Those aged 30 years and above accounted for 63% of the patients, and post-operative sepsis was the most frequently encountered wound infection. Of the organisms encountered, Staphylococcus aureus was the most frequently occurring organism (39%), followed by coliform bacilli (24%), which was the most prevalent organism (44%) in post-operative sepsis. Twenty-one percent of the isolates were Pseudomonas aeruginosa. The majority of the bacterial isolates from the infected wounds were susceptible to Gentamicin, as follows: 92% of the Staph. aureus, 100% of Streptococcus faecalis, Escherichia coli and Pseud. aeruginosa, and 75% of the coliform bacilli. It is suggested that gentamicin, in combination with metronidazole, be used not only for empirical treatment of wound infections in Ekpoma locality but also for prophylactic coverage of surgical operations.
采用标准微生物学方法,以医院患者和非医院患者为对象,对尼日利亚埃克波马地区与伤口感染相关的细菌及其抗菌药敏情况进行了调查。在40名就诊患者中,25名(62.5%)为男性,其余为女性。30岁及以上患者占患者总数的63%,术后败血症是最常见的伤口感染类型。在所发现的微生物中,金黄色葡萄球菌是最常见的菌种(39%),其次是大肠埃希菌(24%),而大肠埃希菌是术后败血症中最普遍的菌种(44%)。21%的分离株为铜绿假单胞菌。感染伤口的大多数细菌分离株对庆大霉素敏感,具体情况如下:92%的金黄色葡萄球菌、100%的粪肠球菌、大肠埃希菌和铜绿假单胞菌,以及75%的大肠埃希菌。建议庆大霉素联合甲硝唑不仅用于埃克波马地区伤口感染的经验性治疗,也用于手术操作的预防性用药。