Faculty of Medicine, Department of Otolaryngology, Cairo University, 7 El Shaheed Mahmoud Afifi St., Almaza, Cairo, Egypt.
Am J Otolaryngol. 2011 Jul-Aug;32(4):308-17. doi: 10.1016/j.amjoto.2010.07.002. Epub 2010 Sep 15.
The objective of the study was to define the true incidence of fungal elements in the nasal and sinus mucous in cases of chronic rhinosinusitis (CRS) with bilateral polyposis compared with normal controls-in an Egyptian African population-via mycological and histologic techniques.
This study was conducted prospectively on 100 patients with the clinical diagnosis of CRS with bilateral nasal polyposis. Fifty volunteers with no history of nasal or paranasal sinus disease served as a control group.
The postulated criteria for the diagnosis of allergic fungal sinusitis were present in 92% of CRS with polyposis, suggesting that fungi are involved in the disease process of most CRS patients.
本研究的目的是通过真菌学和组织学技术，在埃及非洲人群中，与正常对照组相比，定义双侧息肉的慢性鼻-鼻窦炎（CRS）病例中鼻腔和鼻窦黏膜中真菌成分的真实发生率。
本前瞻性研究纳入了 100 例临床诊断为双侧鼻息肉的 CRS 患者。50 名无鼻或鼻旁窦疾病史的志愿者作为对照组。
提出的变应性真菌性鼻旁窦炎的诊断标准在 92%的双侧息肉 CRS 患者中存在，提示真菌参与了大多数 CRS 患者的疾病过程。
