Crawshaw S C, Stocker D I, Sugrue D L, Haran M V
Department of Genitourinary Medicine, Central Outpatients Department, Stoke-on-Trent, UK.
Int J STD AIDS. 1990 May;1(3):191-4. doi: 10.1177/095646249000100308.
Routine screening for sexually transmitted diseases in new patients attending the Genitourinary Clinic in Stoke-on-Trent includes a culture for Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU). A retrospective study was carried out on 400 female patients to ascertain whether there were any significant differences between the group positive for MH and UU and the negative control group. The positive group were found to be younger on average, but to have similar sexual histories to the negative control group. An association was found between the presence of genital mycoplasmas and Gardnerella vaginalis. An odourous vaginal discharge was more common in the positive group. Erythromycin was ineffective in eradicating the organisms in 62.5% of patients with MH, and 70% of those with UU. Continuing work is required to identify those women in whom the presence of MH or UU could have pathogenic effects. Treatment regimens for this group of women need to be carefully reassessed, in the light of increasing antibiotic resistance.
在特伦特河畔斯托克的泌尿生殖科诊所，对新就诊患者进行性传播疾病的常规筛查包括人型支原体（MH）和溶脲脲原体（UU）培养。对400名女性患者进行了一项回顾性研究，以确定MH和UU检测呈阳性的组与阴性对照组之间是否存在显著差异。结果发现，阳性组平均年龄较小，但性病史与阴性对照组相似。发现生殖支原体与阴道加德纳菌之间存在关联。阳性组中出现有异味的阴道分泌物更为常见。在62.5%的MH感染患者和70%的UU感染患者中，红霉素清除这些病原体无效。需要继续开展工作，以确定哪些女性体内的MH或UU可能具有致病作用。鉴于抗生素耐药性不断增加，需要对这组女性的治疗方案进行仔细重新评估。
