基因调控：增强子走出阴影。
Gene regulation: enhancers stepping out of the shadow.
机构信息
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, NY 10032, USA.
出版信息
Curr Biol. 2010 Sep 14;20(17):R697-9. doi: 10.1016/j.cub.2010.07.035.
PMID:20833307
Abstract
The expression of many animal genes has been shown to be controlled by two--rather than one--enhancers with similar regulatory content. Such enhancer redundancy ensures robustness of gene expression under adverse environmental or genetic conditions.
摘要
许多动物基因的表达已被证明是由两个而不是一个具有相似调控内容的增强子控制的。这种增强子冗余确保了基因表达在不利的环境或遗传条件下的稳健性。
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