Brain Imaging Center and Department of Neurology, Goethe University Frankfurt, 60528 Frankfurt, Germany.
Cereb Cortex. 2011 Apr;21(4):932-7. doi: 10.1093/cercor/bhq167. Epub 2010 Sep 10.
Speech production is a left-lateralized brain function, which could arise from a left dominance either in speech executive or sensory processes or both. Using functional magnetic resonance imaging in healthy subjects, we show that sensory cortices already lateralize when speaking is intended, while the frontal cortex only lateralizes when speech is acted out. The sequence of lateralization, first temporal then frontal lateralization, suggests that the functional lateralization of the auditory cortex could drive hemispheric specialization for speech production.
言语产生是一种左脑偏侧化的脑功能，这种偏侧化可能源于言语执行或感觉过程中的左侧优势，或者两者兼有。我们利用功能磁共振成像技术在健康受试者中发现，当意图说话时感觉皮层就已经开始偏侧化，而当实际说话时额叶皮层才开始偏侧化。这种从感觉皮层到额叶皮层的偏侧化顺序表明，听觉皮层的功能偏侧化可能驱动了言语产生的半球专门化。
