与泌乳素瘤相关的精神病的管理：病例报告及文献复习。
Management of psychosis associated with a prolactinoma: case report and review of the literature.
机构信息
McLean Hospital, Boston, MA, USA.
出版信息
Psychosomatics. 2010 Sep-Oct;51(5):370-6. doi: 10.1176/appi.psy.51.5.370.
Abstract
BACKGROUND
Prolactinomas are the most common pituitary tumors; they are treated with dopamine agonists, which may cause psychotic symptoms as a side effect. Psychosis is treated with dopamine-receptor blockers that may result in elevated serum prolactin and symptomatic hyperprolactinemia.
OBJECTIVE
The authors will review a case of a patient with a prolactinoma as well as schizophrenia and illustrate the management of psychosis in this case.
METHOD
The review describes the management of prolactinoma, symptoms of hyperprolactinemia, and long-term effects of hyperprolactinemia.
RESULTS
In the case presentation reviewed, the patient was finally discharged on risperidone long-acting injection and testosterone supplementation, with no growth of the adenoma after 3 years.
DISCUSSION
This review provides recommendations and treatment strategy for management of prolactinoma in a patient with schizophrenia.
摘要
背景
催乳素瘤是最常见的垂体肿瘤；它们用多巴胺激动剂治疗，这可能会导致精神病症状作为副作用。精神病用多巴胺受体阻滞剂治疗，这可能导致血清催乳素升高和症状性高催乳素血症。
目的
作者将回顾一例催乳素瘤、精神分裂症患者的病例，并说明该病例中精神病的治疗方法。
方法
该综述描述了催乳素瘤的管理、高催乳素血症的症状以及高催乳素血症的长期影响。
结果
在回顾的病例介绍中，患者最终接受了利培酮长效注射和睾酮补充治疗，3 年后腺瘤没有生长。
讨论
该综述为精神分裂症患者催乳素瘤的管理提供了建议和治疗策略。
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