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原发性淀粉样变性患者骨闪烁显像中锝99m亚甲基二膦酸盐孤立性异位肺摄取

Isolated ectopic lung uptake of technetium 99m methylene diphosphonate on bone scintigraphy in primary amyloidosis.

作者信息

Zwas S T, Shpilberg O, Huszar M, Rozenman J

机构信息

Department of Nuclear Medicine, Chaim Sheba Medical Centre, Tel Hashomer, Israel.

出版信息

Eur J Nucl Med. 1990;17(5):282-5. doi: 10.1007/BF00812371.

DOI:10.1007/BF00812371
PMID:2083563
Abstract

Pulmonary deposition of technetium 99m methylene diphosphonate was found on a bone scan of a patient with undiagnosed primary AL amyloidosis. Unusual clinical manifestations during the course of the disease led to a post-mortem diagnosis. The mechanisms for pulmonary and other ectopic soft tissue bone scan tracer depositions, as well as their significance in the diagnosis of amyloidosis, are discussed.

摘要

在一名未确诊的原发性AL淀粉样变性患者的骨扫描中发现了锝99m亚甲基二膦酸盐在肺部的沉积。疾病过程中不寻常的临床表现导致了尸检诊断。本文讨论了肺部及其他异位软组织骨扫描示踪剂沉积的机制及其在淀粉样变性诊断中的意义。

相似文献

1
Isolated ectopic lung uptake of technetium 99m methylene diphosphonate on bone scintigraphy in primary amyloidosis.原发性淀粉样变性患者骨闪烁显像中锝99m亚甲基二膦酸盐孤立性异位肺摄取
Eur J Nucl Med. 1990;17(5):282-5. doi: 10.1007/BF00812371.
2
Tc-99m methylene diphosphonate accumulation by a pulmonary hamartoma.肺错构瘤对锝-99m亚甲基二膦酸盐的摄取
Clin Nucl Med. 1998 Oct;23(10):695-6. doi: 10.1097/00003072-199810000-00010.
3
Bone scan in systemic amyloidosis.
Nucl Med Commun. 1988 Nov;9(11):879-90. doi: 10.1097/00006231-198811000-00004.
4
[Cardiac involvement in systemic amyloidosis: myocardial scintigraphic evaluation].[系统性淀粉样变的心脏受累:心肌闪烁显像评估]
J Cardiogr. 1985 Mar;15(1):163-80.
5
[Diagnostic significance of technetium-99m-pyrophosphate, technetium-99m-methylene diphosphonate and gallium-67-citrate scintigraphy in amyloid heart disease--a study with AL amyloidosis and familial amyloid polyneuropathy].[锝-99m-焦磷酸盐、锝-99m-亚甲基二膦酸盐和镓-67-柠檬酸盐闪烁扫描术在淀粉样心脏病中的诊断意义——一项关于AL淀粉样变性和家族性淀粉样多神经病的研究]
Nihon Naika Gakkai Zasshi. 1986 Jan;75(1):1-8. doi: 10.2169/naika.75.1.
6
Amyloidosis of heart and liver: comparison of Tc-99m pyrophosphate and Tc-99m methylene diphosphonate for detection.心脏和肝脏淀粉样变性:锝-99m焦磷酸盐与锝-99m亚甲基二膦酸盐检测的比较
Radiology. 1983 Jul;148(1):239-42. doi: 10.1148/radiology.148.1.6304810.
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Uptake of technetium-99m MDP in primary amyloidosis with a review of the mechanisms of soft tissue localization of bone seeking radiopharmaceuticals.
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Transient myocardial uptake of Tc-99m methylene diphosphonate in a patient with amyloidosis.一名淀粉样变性患者中锝-99m亚甲基二膦酸盐的短暂性心肌摄取。
Am J Med Sci. 1988 Dec;296(6):413-6. doi: 10.1097/00000441-198812000-00008.
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Pulmonary uptake of Tc-99m-Labeled methylene diphosphonate in a patient with a parathyroid adenoma.
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Tc-99m HDP uptake in cardiac amyloidosis.锝-99m亚甲基二膦酸盐在心脏淀粉样变性中的摄取
Clin Nucl Med. 1999 Mar;24(3):156-8. doi: 10.1097/00003072-199903000-00002.

引用本文的文献

1
Unusual Focal Lung Uptake without CT Abnormality on a Bone Scan: What Might It Mean?骨扫描显示肺部局灶性摄取异常但CT无异常:这意味着什么?
Diagnostics (Basel). 2022 Apr 8;12(4):934. doi: 10.3390/diagnostics12040934.
2
Demonstration of primary tracheobronchial amyloidosis by 99mTc-HMDP bone SPECT.
Ann Nucl Med. 1993 Nov;7(4):269-72. doi: 10.1007/BF03164709.

本文引用的文献

1
Primary systemic amyloidosis.原发性系统性淀粉样变性
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Demonstration of AA-protein in formalin-fixed, paraffin-embedded tissues.在福尔马林固定、石蜡包埋组织中AA蛋白的显示
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Diffusely increased Tc-99m-MDP uptake in both kidneys.
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Amyloidosis (AL). Clinical and laboratory features in 229 cases.淀粉样变性(AL型)。229例患者的临床及实验室特征。
Mayo Clin Proc. 1983 Oct;58(10):665-83.
5
Amyloidosis of heart and liver: comparison of Tc-99m pyrophosphate and Tc-99m methylene diphosphonate for detection.心脏和肝脏淀粉样变性:锝-99m焦磷酸盐与锝-99m亚甲基二膦酸盐检测的比较
Radiology. 1983 Jul;148(1):239-42. doi: 10.1148/radiology.148.1.6304810.
6
Sensitivity of technetium-99m-pyrophosphate scintigraphy in diagnosing cardiac amyloidosis.锝-99m焦磷酸盐闪烁扫描术在诊断心脏淀粉样变性中的敏感性。
Am J Cardiol. 1983 Mar 1;51(5):826-30. doi: 10.1016/s0002-9149(83)80140-4.
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Soft tissue uptake of bone seeking radionuclide in amyloidosis.淀粉样变性中亲骨性放射性核素的软组织摄取。
J Rheumatol. 1981 Sep-Oct;8(5):760-6.
8
Amyloid goiter: preoperative scintigraphic diagnosis using Tc-99m pyrophosphate.淀粉样甲状腺肿:使用锝-99m焦磷酸盐进行术前闪烁扫描诊断。
J Nucl Med. 1984 Apr;25(4):468-71.
9
The lung in generalized amyloidosis.全身性淀粉样变性中的肺脏。
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Diagnosis of pulmonary amyloidosis by transbronchial biopsy.经支气管活检诊断肺淀粉样变性
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