Khromov A S, Sagach V F, Dmitrieva A V, Doloman L B
Fiziol Zh (1978). 1990 Nov-Dec;36(6):13-7.
The main parameters of hemodynamic and myocardial contractile activity, transcapillary fluid and proteins exchange have been studied in healthy and infected anaesthetized dogs with source of purulent infection during septic shock development. Besides, blood gas tension, pH and toxicity of blood and lymph are determined as well. It is shown that damage of microcirculation promoting tissue hypoxia and endogenous intoxication, is responsible for the initiation of decompensating disturbance of circulation at pus process generalization.
在脓毒性休克发展过程中，对健康和感染的麻醉犬（伴有脓性感染源）的血流动力学和心肌收缩活动的主要参数、跨毛细血管液体和蛋白质交换进行了研究。此外，还测定了血液气体张力、pH值以及血液和淋巴的毒性。结果表明，微循环损伤促进组织缺氧和内源性中毒，是在脓毒症过程扩散时引发循环代偿失调的原因。
