Department of Hematology/Oncology/Palliative Care, Mayo Clinic Arizona, Phoenix, Arizona 85054, USA.
J Palliat Med. 2010 Sep;13(9):1159-62. doi: 10.1089/jpm.2009.0418.
Disorders in which the effects of cancer occur at a site remote from the primary tumor are termed paraneoplastic disorders. The most well- known paraneoplastic disorder affecting the neuromuscular junction is the Lambert-Eaton myasthenic syndrome (LEMS).
We describe a case of the Lambert-Eaton myasthenic syndrome diagnosed in a patient with small cell lung cancer presenting with profound weakness. The discussion that follows the case describes the pathophysiology of the disorder, clinical characteristics and therapies that have been used. The role of the palliative care team in the case is described.
在远离原发性肿瘤的部位发生癌症影响的疾病被称为副肿瘤性疾病。最著名的影响神经肌肉接头的副肿瘤性疾病是 Lambert-Eaton 肌无力综合征（LEMS）。
我们描述了一例在小细胞肺癌患者中诊断出的 Lambert-Eaton 肌无力综合征病例，该患者表现为严重无力。随后的讨论描述了该疾病的病理生理学、临床特征和已使用的治疗方法。还描述了姑息治疗团队在该病例中的作用。
