美国临床肿瘤学会 2010 年：中枢神经系统肿瘤部分精选研究报告。
American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section.
机构信息
Division of Cancer Neurology, Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
出版信息
Expert Rev Anticancer Ther. 2010 Sep;10(9):1367-9. doi: 10.1586/era.10.117.
A number of important studies were presented at the CNS tumors section of the 2010 American Society of Oncology (ASCO) Annual Meeting. There was particular interest in a Phase II study showing that the mTOR inhibitor everolimus had significant activity in tuberous patients with subependymal giant cell astrocytomas. Two Phase III studies reported on the relative benefits of radiotherapy and chemotherapy in elderly patients with glioblastomas. Other studies focused on promising new agents such as XL184 and ANG1005.
一些重要的研究在 2010 年美国肿瘤学会（ASCO）年会上的中枢神经系统肿瘤分会进行了展示。特别引人关注的是一项 II 期研究表明，mTOR 抑制剂依维莫司在室管膜下巨细胞星形细胞瘤的结节性硬化症患者中具有显著活性。两项 III 期研究报告了放疗和化疗在老年胶质母细胞瘤患者中的相对益处。其他研究则侧重于有前途的新药物，如 XL184 和 ANG1005。
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