Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2010 Sep;26(9):496-501. doi: 10.1016/S1607-551X(10)70078-4.
Intrathoracic tumor is a rare entity in the pediatric population and neurogenic tumors account for 40-50% of childhood intrathoracic tumors. They can cause severe symptoms, such as respiratory distress, neurological dysfunction and metabolic disturbances. Posterior mediastinal ganglioneuroma (GN) usually occurs in children and can be found accidentally. Precise preoperative diagnosis is very difficult and has a great influence on surgical intervention. Here, we report a 6-year-old girl with a posterior mediastinal GN that was found incidentally on chest radiography. Computed tomography and magnetic resonance imaging demonstrated a right paraspinal tumor with punctuate calcification and intraspinal extension. (18)F-fluorodeoxyglucose positron emission tomography revealed low-grade fluorodeoxyglucose avidity of this tumor. Computed tomography and magnetic resonance imaging can characterize GN and positron emission tomography is helpful for differentiating benign or malignant lesions.
胸腔内肿瘤在儿科人群中较为罕见,神经源性肿瘤占儿童胸腔内肿瘤的 40-50%。它们可引起严重的症状,如呼吸困难、神经功能障碍和代谢紊乱。后纵隔神经节瘤(GN)通常发生于儿童,可偶然发现。精确的术前诊断非常困难,并对手术干预有重大影响。在此,我们报告了一例 6 岁女孩,其因胸片偶然发现后纵隔 GN。计算机断层扫描和磁共振成像显示右侧脊柱旁肿瘤,有点状钙化和椎管内延伸。(18)F-氟脱氧葡萄糖正电子发射断层扫描显示该肿瘤低度氟脱氧葡萄糖摄取。计算机断层扫描和磁共振成像有助于 GN 的特征化,而正电子发射断层扫描有助于区分良性或恶性病变。