Ivanov E P, Levin V I, Smirnova L A, Molochko V A
Gematol Transfuziol. 1990 Dec;35(12):23-4.
The level of ABO(H) antigen expression was estimated on erythrocytes isolated from the peripheral blood of 94 leukemia patients. The control group included 1014 blood donors. It was found that the level of H antigen expression was lowered in all forms of leukemia, while the levels of A and B antigen expression were unchanged. It has been suggested that the lowering of H antigen expression level is a pathogenetic sign of the leukemic process, and its value could be used for the control of the disease course character.
对94例白血病患者外周血分离出的红细胞上ABO(H)抗原表达水平进行了评估。对照组包括1014名献血者。结果发现,在所有白血病类型中H抗原表达水平均降低,而A和B抗原表达水平未变。有人提出,H抗原表达水平降低是白血病进程的致病标志,其数值可用于控制疾病进程特点。