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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Pigolkin J I, Volodin S A, Sherstyuk B V, Bozhko G G

Department for Problems of the Regulation of Biological Processes, Far Eastern Section of the Academy of Sciences, Vladivostok, USSR.

Folia Morphol (Praha). 1990;38(4):321-6.

Morphohistological changes in a focus of spinal cord trauma have a phasic character, with a period of primary lesions (5-30 min after traumatization) and a period of secondary lesions (1-23 h after traumatization). 2. Variation of transport enzyme activities in the walls of the microvessels of the traumatized spinal cord is characterized by an undulating course and by asynchrony of the peaks of Mg-dependent ATPase and alkaline phosphatase activity. 3. With reference to the rapid drop in the given enzyme activities and to progressive necrotic changes in the traumatized spinal cord, it is desirable that the cord circulation should be corrected within the first few hours after traumatization.

脊髓创伤灶的形态组织学变化具有阶段性，包括原发性损伤期（创伤后5 - 30分钟）和继发性损伤期（创伤后1 - 23小时）。2. 创伤脊髓微血管壁中转运酶活性的变化特点是呈波浪状过程，且镁依赖性ATP酶和碱性磷酸酶活性峰值不同步。3. 鉴于上述酶活性的快速下降以及创伤脊髓中进行性坏死性变化，理想的情况是在创伤后的最初几小时内纠正脊髓循环。

Pigolkin J I, Volodin S A, Sherstyuk B V, Bozhko G G

Department for Problems of the Regulation of Biological Processes, Far Eastern Section of the Academy of Sciences, Vladivostok, USSR.

Folia Morphol (Praha). 1990;38(4):321-6.

Morphohistological changes in a focus of spinal cord trauma have a phasic character, with a period of primary lesions (5-30 min after traumatization) and a period of secondary lesions (1-23 h after traumatization). 2. Variation of transport enzyme activities in the walls of the microvessels of the traumatized spinal cord is characterized by an undulating course and by asynchrony of the peaks of Mg-dependent ATPase and alkaline phosphatase activity. 3. With reference to the rapid drop in the given enzyme activities and to progressive necrotic changes in the traumatized spinal cord, it is desirable that the cord circulation should be corrected within the first few hours after traumatization.

脊髓创伤灶的形态组织学变化具有阶段性，包括原发性损伤期（创伤后5 - 30分钟）和继发性损伤期（创伤后1 - 23小时）。2. 创伤脊髓微血管壁中转运酶活性的变化特点是呈波浪状过程，且镁依赖性ATP酶和碱性磷酸酶活性峰值不同步。3. 鉴于上述酶活性的快速下降以及创伤脊髓中进行性坏死性变化，理想的情况是在创伤后的最初几小时内纠正脊髓循环。