Department of Family Medicine & Public Health Sciences, Division of Occupation and Environmental Health, Wayne State University School of Medicine, 3939 Woodward Ave., 3rd floor, Detroit, MI 48201, USA.
J Immigr Minor Health. 2011 Jun;13(3):568-75. doi: 10.1007/s10903-010-9390-0.
Although the prevalence of asthma is increasing worldwide, there are striking, and largely unexplained differences across various racial and ethnic groups. The current study looks at the prevalence of asthma and risk factors between Chaldeans, Arabs, and African Americans. We used Health Assessment Survey data representing 3,136 respondents. Prevalence across the three ethnic groups were compared using unadjusted and adjusted odds ratios, accounting for multiple risk factors. There were significant socio-demographic differences across all ethnic groups. Asthma prevalence was significantly lower in Arabs (9.4%) and Chaldeans (5.4%) than in Non-Middle Eastern Whites (14.4%). African American prevalence was 14.4%. The significantly lower prevalence of asthma among Chaldean and Arabs, as compared to African Americans, were not explained by traditional risk factors included in our models. We therefore, suggest that future studies should explore the possible role of ethnic-specific differences in gene × environmental interactions in the precipitation and/or exacerbation of asthma.
尽管哮喘的患病率在全球范围内呈上升趋势,但在不同种族和族裔群体中存在着显著的、在很大程度上尚未得到解释的差异。本研究旨在探讨迦勒底人、阿拉伯人和非裔美国人之间哮喘的患病率和危险因素。我们使用了代表 3136 名受访者的健康评估调查数据。在考虑了多种危险因素后,使用未经调整和调整后的优势比比较了这三个种族群体的患病率。所有种族群体之间都存在显著的社会人口统计学差异。与非中东白人(14.4%)相比,阿拉伯人(9.4%)和迦勒底人(5.4%)的哮喘患病率明显较低。非裔美国人的患病率为 14.4%。与非裔美国人相比,迦勒底人和阿拉伯人哮喘患病率明显较低,这不能用我们模型中包含的传统危险因素来解释。因此,我们建议未来的研究应该探讨种族特异性基因与环境相互作用差异在哮喘的发生和/或恶化中的可能作用。