Venkataraman S, Roy A K, Dhamija R M, Sanchetee P C
Neurological Centre, Army Hospital, Delhi Cantt.
J Assoc Physicians India. 1990 Oct;38(10):763-5.
Meningoencephalitic syndrome can be caused by many infective agents. Over a period of 13 years, 15 of 170 cases of neurocysticercosis (NCC) presented as meningoencephalitis. The basis of diagnosis of NCC was positive subcutaneous nodule histopathology (4), CT scan (9) and autopsy (3) findings. The age of the patients ranged from 7-68 years (mean 32). Fever was encountered in 12, altered sensorium in 7, seizures in 10 and abnormal behaviour in 3 cases. All cases had papilloedema. Focal neurological signs included optic atrophy, lateral rectus palsy, hemiplegia, internuclear ophthalmoplegia and cerebellar ataxia. Cerebrospinal fluid was abnormal in 8 of 13 cases, leading to a suspicion of tuberculous meningitis. Twelve patients improved with therapy. Three cases ended fatally and autopsy confirmed the diagnosis.
脑膜脑炎综合征可由多种感染因素引起。在13年的时间里,170例神经囊尾蚴病(NCC)中有15例表现为脑膜炎。NCC的诊断依据为皮下结节组织病理学检查阳性(4例)、CT扫描(9例)及尸检(3例)结果。患者年龄在7至68岁之间(平均32岁)。12例有发热,7例有意识改变,10例有癫痫发作,3例有行为异常。所有病例均有视乳头水肿。局灶性神经体征包括视神经萎缩、外直肌麻痹、偏瘫、核间性眼肌麻痹和小脑共济失调。13例中有8例脑脊液异常,导致怀疑为结核性脑膜炎。12例患者经治疗后好转。3例死亡,尸检确诊。