Department of Dermatology, Ghent University Hospital, Belgium.
Arch Dermatol Res. 2011 Jan;303(1):57-63. doi: 10.1007/s00403-010-1082-z. Epub 2010 Sep 15.
Chronic inflammatory skin disorders have a major impact on the patients' health related quality of life. Preliminary studies to date have suggested that additional educational and psychological training programmes may be effective in the management of chronic skin diseases, although more rigid methodology is needed. Our purpose was to investigate the effect on quality of life of a novel multidisciplinary educational programme for patients, 18 years or older, with chronic skin diseases. The 12-week intervention encompasses cognitive education on skin and general health issues, and stress-reducing techniques. Quality of life questionnaires were used to assess the participants at baseline and at the end of the program. These comprehend Dermatology Life Quality Index (DLQI), Skindex-29, Psoriasis Disability Index (PDI) and Quality of Life Index for Atopic Dermatitis (QoLIAD). Fifty-five patients participated in six programmes since 2006. Forty-three patients completed the programme. Overall, compared to baseline, DLQI (n = 39) improved by 5.64 points (p < 0.001; SD ±6.09), Skindex-29 (n = 27) by 19.67 points (p < 0.001; SD ±17.37), PDI (n = 9) improved by 7.44 points (p = 0.019; SD ±7.60) and QoLIAD (n = 13) improved by 4.39 points (p = 0.036; SD ±6.69) by the end of the intervention. Preliminary results show that the quality of life of the patients with chronic skin diseases improved significantly after participation to the programme. These positive initial results are stimulating to set up a prospective controlled randomised trial investigating the impact on quality of life, the clinical efficacy and the cost-effectiveness of this educational intervention programme.
慢性炎症性皮肤病对患者的生活质量有重大影响。迄今为止的初步研究表明,额外的教育和心理培训计划可能对慢性皮肤病的治疗有效,尽管需要更严格的方法。我们的目的是研究一种针对慢性皮肤病患者(18 岁及以上)的新型多学科教育计划对生活质量的影响。该 12 周的干预措施包括皮肤和一般健康问题的认知教育,以及减轻压力的技术。使用生活质量问卷在基线和项目结束时评估参与者。这些问卷包括皮肤病生活质量指数(DLQI)、Skindex-29、银屑病残疾指数(PDI)和特应性皮炎生活质量指数(QoLIAD)。自 2006 年以来,有 55 名患者参加了 6 个项目。有 43 名患者完成了该项目。总体而言,与基线相比,DLQI(n = 39)改善了 5.64 分(p < 0.001;SD ±6.09),Skindex-29(n = 27)改善了 19.67 分(p < 0.001;SD ±17.37),PDI(n = 9)改善了 7.44 分(p = 0.019;SD ±7.60),QoLIAD(n = 13)改善了 4.39 分(p = 0.036;SD ±6.69)。初步结果表明,参加该项目后,慢性皮肤病患者的生活质量显著改善。这些积极的初步结果激发了我们设立一项前瞻性对照随机试验,以研究该教育干预计划对生活质量、临床疗效和成本效益的影响。