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丙烯酰胺的毒性及其在婴儿食品中暴露量的评估。

Toxicity of acrylamide and evaluation of its exposure in baby foods.

机构信息

Department of Toxicology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.

出版信息

Nutr Res Rev. 2010 Dec;23(2):323-33. doi: 10.1017/S0954422410000211. Epub 2010 Sep 16.

Abstract

Contaminants are a vast subject area of food safety and quality and can be present in our food chain from raw materials to finished products. Acrylamide, an α,β-unsaturated (conjugated) reactive molecule, can be detected as a contaminant in several foodstuffs including baby foods and infant formulas. It is anticipated that children will generally have intakes that are two to three times those of adults when expressed on a body-weight basis. Though exposure to acrylamide is inevitable, it is necessary to protect infant and children from high exposure. The present review focuses on the several adverse health effects of acrylamide including mutagenicity, genotoxicity, carcinogenicity, neurotoxicity and reproductive toxicity, and the possible outcomes of childhood exposure from baby foods and infant formulas.

摘要

污染物是食品安全和质量的一个广泛领域,它们可能存在于我们的食物链中,从原材料到成品。丙烯酰胺是一种α,β-不饱和(共轭)反应性分子,可作为几种食品(包括婴儿食品和婴儿配方奶粉)中的污染物被检出。预计儿童的摄入量按体重计算将是成年人的两到三倍。虽然接触丙烯酰胺是不可避免的,但有必要保护婴儿和儿童免受高暴露的影响。本综述重点介绍了丙烯酰胺的几种不良健康影响,包括致突变性、遗传毒性、致癌性、神经毒性和生殖毒性,以及婴儿食品和婴儿配方奶粉中儿童暴露的可能后果。

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