Weingertner Anne Sophie, Wilt Marc, Atallah Ihab, Fohrer Cécile, Mauvieux Laurent, Rodier Jean-François
Department of Surgical Oncology, Centre Paul Strauss, Strasbourg, France.
Case Rep Oncol. 2009 Jan 17;2(1):1-6. doi: 10.1159/000191215.
The development of acute myeloid leukaemia after low-dose radioiodine therapy and its presentation as a myeloid sarcoma of the uterine cervix are both rare events. We report a case of acute myeloid leukaemia revealed by a myeloid sarcoma of the uterine cervix in a 48-year-old woman, 17 months after receiving a total dose of 100 mCi (131)I for papillary thyroid cancer. A strict hematological follow-up of patients treated with any dose of (131)I is recommended to accurately detect any hematological complications which might have been underestimated. Unusual presentations, such as chloroma of the uterine cervix, may reveal myeloid malignancy and should be kept in mind.
低剂量放射性碘治疗后发生急性髓系白血病并表现为宫颈髓系肉瘤均为罕见事件。我们报告一例48岁女性，在接受100毫居里（131）I全剂量治疗乳头状甲状腺癌17个月后，宫颈髓系肉瘤引发急性髓系白血病。建议对接受任何剂量（131）I治疗的患者进行严格的血液学随访，以准确检测任何可能被低估的血液学并发症。不寻常的表现，如宫颈绿色瘤，可能提示髓系恶性肿瘤，应予以重视。
