Tabibi Ali, Abdi Hamidreza, Mahmoudnejad Nastaran
Urology and Nephrology Research Center, Shahid Labbafinejad Medical Center, Shahid Beheshti University, MC, Tehran, Iran.
Urol J. 2010 Summer;7(3):174-7.
To compare erectile function following low flow priapism in patients undergoing distal and proximal shunts.
From January 1995 to December 2005, we retrospectively studied 16 patients who presented to our medical center with refractory priapism. Of 16 patients, 5 underwent Winter shunt, while El-Ghorab procedure was performed for 7 patients and the remaining 4 underwent Grayhack shunt. Erectile function was assessed in a minimum follow-up of 2 years (range, 2 to 10 years) using erectile dysfunction (ED) intensity scale [Total score: 5 to 10 (severe ED); 11 to 15 (moderate ED); 16 to 20 (mild ED); and 21 to 25 (no ED)].
The mean patient's age was 40.62 ± 15.27 years. Mean duration of priapism was 51.12 ± 37.99 hours. Of 4 patients (25%) who underwent proximal shunt (Grayhack procedure), 2 (50%) were impotent, 1 had potency, and the other one achieved some penile erection with administration of oral sildenafil. Of 5 patients (31.25%) who underwent Winter procedure, 1 died because of metastatic bladder cancer and of 4 remainders, 2 (50%) had normal erectile function, but 1 patient suffered from recurrent priapism. Of 7 patients (43.75%) who underwent El-Ghorab procedure, 1 was lost for follow-up and of remaining 6 patients, 2 (33.3%) had normal erectile function and 4 (66.6%) were impotent. No surgical complication was seen. Median lag time from priapism till surgery for patients with and without ED was 48 and 26 hours, respectively (P = .22).
Grayhack shunt is a safe surgical procedure without any major complications and with lower ED rate. Grayhack shunt might be considered as treatment of choice for refractory low flow priapism.
比较接受远端分流术和近端分流术的患者在低流量阴茎异常勃起后的勃起功能。
1995年1月至2005年12月,我们对16例因难治性阴茎异常勃起前来我院治疗的患者进行了回顾性研究。16例患者中,5例行温特分流术,7例行埃尔-戈拉布手术,其余4例行格雷哈克分流术。采用勃起功能障碍(ED)强度量表在至少2年(范围为2至10年)的随访中评估勃起功能[总分:5至10分(重度ED);11至15分(中度ED);16至20分(轻度ED);21至25分(无ED)]。
患者平均年龄为40.62±15.27岁。阴茎异常勃起的平均持续时间为51.12±37.99小时。在接受近端分流术(格雷哈克手术)的4例患者(25%)中,2例(50%)阳痿,1例有勃起功能,另1例在服用口服西地那非后阴茎有一定勃起。在接受温特手术的5例患者(31.25%)中,1例因转移性膀胱癌死亡,其余4例中,2例(50%)勃起功能正常,但1例患者复发性阴茎异常勃起。在接受埃尔-戈拉布手术的7例患者(43.75%)中,1例失访,其余6例中,2例(33.3%)勃起功能正常,4例(66.6%)阳痿。未观察到手术并发症。有ED和无ED患者从阴茎异常勃起至手术的中位间隔时间分别为第 = 48小时和26小时(P = 0.22)。
格雷哈克分流术是一种安全的手术方法,无任何重大并发症,ED发生率较低。格雷哈克分流术可被视为难治性低流量阴茎异常勃起的首选治疗方法。