Marjanović Ivan, Jevtić Miodrag, Misović Sidor, Colić Miodrag, Zoranović Uros, Sarac Momir, Rusović Sinisa, Jovanović Milan
Vojnomedicinska akademija, Klinika za vaskularnu hirurgiju, Beograd, Srbija.
Vojnosanit Pregl. 2010 Aug;67(8):665-73. doi: 10.2298/vsp1008665m.
BACKGROUND/AIM: Surgical treatment is the only method of abdominal aorta aneurysm (AAA) treatment. According to data of the available literature, elective open, i.e., conservative, reconstruction (OR) is followed by 3%-5% mortality, as well as by numerous comorbide conditions inside the early postoperative course (the first 30 days after the surgery) that occur in 20%-30% of the operated on. The aim of the study was to present preliminar results of a comparative clinical retrospective study of early postoperative morbidity and mortality in AAA reconstruction using endovascular (EVAR) and open surgical techniques.
This comparative clinical retrospective study included 59 patients, electively operated on for AAA within the period January 2008-March 2009, divided into two groups. The group I counted 29 (49%) of the patients who had been submitted to EVAR by the use of Excluder stent. The group II consisted of 30 (51%) of the patients operated on using OR. All of the patients were males, 50-87 years old (mean 67.6 year in the group I, and 54-86 years (mean 68.3 years) in the group II. All tha patients had AAA larger than 50 mm, in the group I 50-105 mm (mean 68 mm), and in the group II 50-84 mm (mean 65 mm). Preoperative comorbide conditions of any patients were similar (coronary disease, obstructive lung disease, chronical renal insufficiency). Patients operated on as emergency cases due to rupture or due to symptomatic aneurysm (threthening rupture) were excluded. The analysed parameters were the duration of surgical operation, intraoperative and operative blood substitution, postoperative morbidity, the duration of postoperative hospitalization, and hospital mortality.
The obtained results showed a statistically significantly shorter time taken by EVAR surgery (average 95 min, ranging 70-180 min) as compared to OR surgery (average 167 min, ranging 90-300 min). They also showed statistically significantly less blood loss in the patients operated on by the use of EVAR surgery (average blood compensation 130 mL, ranging 0-1050 mL) as compared to OR surgery (average blood compensation 570 mL, ranging 0-2.000 mL). Also, general complications as wound infection, no restoration of intestines peristalsis, febrility, proteinic and electolytic disbalance, lung and heart decompensation were statistically significantly less following EVAR than OR surgery. Postoperative hospitalization was also statistically significantly shorter after EVAR than after OR surgery (average 4.2 days, ranging 3-7 days; 10.6 days, ranging 8-35 days, respectively). Finally, within this 13-month study there was no mortality following EVAR surgery, while two patients died after OR surgery.
In the patients with elective AAA reconstruction endovascular reconstruction is shown to be far more safer and minimally invasive procedure than open conventional aorta reconstruction.
背景/目的:手术治疗是腹主动脉瘤(AAA)治疗的唯一方法。根据现有文献数据,择期开放性即保守性重建术(OR)的死亡率为3%-5%,并且在术后早期病程(术后前30天)中,20%-30%的手术患者会出现多种合并症。本研究的目的是展示一项关于使用血管内(EVAR)和开放手术技术进行AAA重建术后早期发病率和死亡率的比较临床回顾性研究的初步结果。
这项比较临床回顾性研究纳入了59例在2008年1月至2009年3月期间因AAA接受择期手术的患者,分为两组。第一组有29例(49%)患者接受了使用Excluder支架的EVAR治疗。第二组由30例(51%)接受OR手术的患者组成。所有患者均为男性,年龄在50 - 87岁之间(第一组平均67.6岁,第二组54 - 86岁,平均68.3岁)。所有患者的AAA直径大于50mm,第一组为50 - 105mm(平均68mm),第二组为50 - 84mm(平均65mm)。任何患者的术前合并症相似(冠心病、阻塞性肺病、慢性肾功能不全)。因破裂或有症状性动脉瘤(有破裂风险)而作为急诊手术的患者被排除。分析的参数包括手术时间、术中及手术中的输血情况、术后发病率、术后住院时间和医院死亡率。
获得的结果显示,与OR手术(平均167分钟,范围90 - 300分钟)相比,EVAR手术所需时间在统计学上显著更短(平均95分钟,范围70 - 180分钟)。结果还显示,与OR手术(平均输血570mL,范围0 - 2000mL)相比,接受EVAR手术的患者术中失血量在统计学上显著更少(平均输血130mL,范围0 - 1050mL)。此外,常见并发症如伤口感染、肠道蠕动未恢复、发热、蛋白质和电解质失衡、肺和心脏失代偿在EVAR术后比OR手术在统计学上显著更少。EVAR术后的住院时间在统计学上也显著短于OR手术(分别为平均4.2天,范围3 - 7天;10.6天,范围8 - 35天)。最后,在这项为期13个月的研究中,EVAR手术后无死亡病例,而OR手术后有2例患者死亡。
对于择期AAA重建患者,血管内重建术被证明比传统开放性主动脉重建术更安全且创伤更小。