Godard J, Jacquet G, Pageaut G, Farhat O, Steimle R
Service de Neurochirurgie, CHU Jean Minjoz, Besançon.
Neurochirurgie. 1990;36(6):388-93.
The chordomas are malignant tumors arising from the remnants of the posterior spinal chord. The chordomas of the cervical spine are rare (5% of the spinal chordomas). A new case of spine chordoma at C5 level in a 76 years old woman is reported. The diagnosis depends on the results of the histological studies and especially the studies of the labelled elements as Protein S100 or Cytokeratin. Firstly a double osteosynthesis was realized by an anterior and posterior approach. There was no radiotherapy after this operation. A new operation for a fracture of odontoid process was necessary one year later. There was no recurrence. The patient was complaining from pains, two years after the first operation in relation to lateral recurrence. A third operation by an anterior approach was realized. A radiotherapy of 50 Gy was applied on the same level. The first osteosynthesis was with acrylic cement and the second one with an autologous bone graft and a plate after removing the cement without problem. Actually she is in good health, 78 years old.
脊索瘤是起源于脊髓后部残余组织的恶性肿瘤。颈椎脊索瘤罕见(占脊髓脊索瘤的5%)。本文报道了一例76岁女性C5水平脊柱脊索瘤的新病例。诊断依赖于组织学研究结果,尤其是对标记物如蛋白S100或细胞角蛋白的研究。首先通过前后联合入路进行了双钢板内固定术。术后未进行放疗。一年后因齿状突骨折需要再次手术。未出现复发。首次手术后两年,患者因侧方复发出现疼痛。遂通过前路进行了第三次手术。在同一水平给予了50 Gy的放疗。第一次内固定使用丙烯酸骨水泥,第二次在取出骨水泥后使用自体骨移植和钢板,未出现问题。实际上,她现在78岁,身体健康。