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[新型抗流感药物研发的现状与未来]

[Present and future in development of new anti-influenza drugs].

作者信息

Watanabe Akira

机构信息

Research Division for Development of Anti-Infective Agents, Institute of Development, Aging and Cancer, Tohoku University.

出版信息

Nihon Rinsho. 2010 Sep;68(9):1685-9.

Abstract

Against pandemic influenza A (H1N1) 2009, anti-influenza drugs were useful to save the disease aggravation and reduce the mortality. In addition to the existing anti-influenza drugs, novel drugs, including neuraminidase inhibitors (peramivir and laninamivir) and RNA polymerase inhibitors (favipiravir), also have clinical potentials to suppress pandemic influenza A (H1N1) 2009 virus as well as seasonal influenza virus.

摘要

针对2009年甲型H1N1流感大流行,抗流感药物有助于挽救病情恶化并降低死亡率。除现有的抗流感药物外,新型药物,包括神经氨酸酶抑制剂(帕拉米韦和拉尼米韦)和RNA聚合酶抑制剂(法匹拉韦),也具有抑制2009年甲型H1N1流感大流行病毒以及季节性流感病毒的临床潜力。

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