Wu Stephanie C, Marston William, Armstrong David G
Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
J Am Podiatr Med Assoc. 2010 Sep-Oct;100(5):385-94. doi: 10.7547/1000385.
Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. Although major hurdles remain, advances during the past generation have improved the clinician's armamentarium in the medical and surgical management of this problem. The purpose of this article is to review the current literature regarding the pragmatic use of three of the most commonly used advanced therapies: bioengineered tissue, negative-pressure wound therapy, and hyperbaric oxygen therapy, with a focus on the near-term future of wound healing, including stem cell therapy.
伤口修复与再生是基质破坏与重组的高度复杂组合。尽管仍存在重大障碍,但过去一代人取得的进展已改善了临床医生在该问题的医学和外科治疗方面的手段。本文旨在回顾有关三种最常用先进疗法实际应用的当前文献:生物工程组织、负压伤口治疗和高压氧治疗,重点关注伤口愈合的近期未来,包括干细胞治疗。