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伤口护理:先进伤口愈合技术的作用

Wound care: the role of advanced wound-healing technologies.

作者信息

Wu Stephanie C, Marston William, Armstrong David G

机构信息

Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.

出版信息

J Am Podiatr Med Assoc. 2010 Sep-Oct;100(5):385-94. doi: 10.7547/1000385.

DOI:10.7547/1000385
PMID:20847352
Abstract

Wound repair and regeneration is a highly complex combination of matrix destruction and reorganization. Although major hurdles remain, advances during the past generation have improved the clinician's armamentarium in the medical and surgical management of this problem. The purpose of this article is to review the current literature regarding the pragmatic use of three of the most commonly used advanced therapies: bioengineered tissue, negative-pressure wound therapy, and hyperbaric oxygen therapy, with a focus on the near-term future of wound healing, including stem cell therapy.

摘要

伤口修复与再生是基质破坏与重组的高度复杂组合。尽管仍存在重大障碍,但过去一代人取得的进展已改善了临床医生在该问题的医学和外科治疗方面的手段。本文旨在回顾有关三种最常用先进疗法实际应用的当前文献:生物工程组织、负压伤口治疗和高压氧治疗,重点关注伤口愈合的近期未来,包括干细胞治疗。

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1
Wound care: the role of advanced wound-healing technologies.伤口护理:先进伤口愈合技术的作用
J Am Podiatr Med Assoc. 2010 Sep-Oct;100(5):385-94. doi: 10.7547/1000385.
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Wound care: the role of advanced wound healing technologies.伤口护理:先进伤口愈合技术的作用。
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Bioengineered alternative tissues and hyperbaric oxygen in lower extremity wound healing.生物工程替代组织与高压氧在下肢伤口愈合中的应用
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Innovation and management of diabetic foot wounds.糖尿病足伤口的创新与管理。
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Critiquing clinical research of new technologies for diabetic foot wound management.对糖尿病足伤口管理新技术的临床研究进行批判。
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Surgical soft tissue closure of severe diabetic foot infections: a combination of biologics, negative pressure wound therapy, and skin grafting.严重糖尿病足感染的手术软组织闭合:生物制品、负压伤口治疗和皮肤移植的联合应用。
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Effectiveness of interventions to enhance healing of chronic ulcers of the foot in diabetes: a systematic review.干预措施对增强糖尿病患者足部慢性溃疡愈合效果的影响:系统评价。
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Bioengineered alternative tissues in diabetic wound healing.生物工程替代组织在糖尿病伤口愈合中的应用
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Wound healing. New modalities for a new millennium.伤口愈合。新千年的新模式。
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An evaluation of healing metrics associated with commonly used advanced wound care products for the treatment of chronic diabetic foot ulcers.对用于治疗慢性糖尿病足溃疡的常用高级伤口护理产品相关愈合指标的评估。
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引用本文的文献

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Stem cell therapy: a promising frontier in modern medicine with a comprehensive overview of their biology and potential therapeutic applications in chronic non-healing cutaneous injuries.干细胞疗法:现代医学中一个充满前景的前沿领域,全面概述其生物学特性以及在慢性难愈性皮肤损伤中的潜在治疗应用。
Inflammopharmacology. 2025 Sep 4. doi: 10.1007/s10787-025-01924-6.
2
Developing and Establishing a Wound Dressing Team: Experience and Recommendations.发展和建立伤口敷料团队:经验与建议。
J Korean Med Sci. 2023 May 29;38(21):e168. doi: 10.3346/jkms.2023.38.e168.
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Analysis of the size reduction of AgNPs loaded hydrogel and its effect on the anti-bacterial activity.
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IET Nanobiotechnol. 2021 Aug;15(6):545-557. doi: 10.1049/nbt2.12037. Epub 2021 Mar 22.
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The effect of continuous diffusion of oxygen treatment on cytokines, perfusion, bacterial load, and healing in patients with diabetic foot ulcers.持续氧气扩散治疗对糖尿病足溃疡患者细胞因子、灌注、细菌负荷和愈合的影响。
Int Wound J. 2020 Dec;17(6):1986-1995. doi: 10.1111/iwj.13490. Epub 2020 Aug 24.
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Negative pressure wound therapy compared with standard moist wound care on diabetic foot ulcers in real-life clinical practice: results of the German DiaFu-RCT.负压伤口疗法与标准湿性伤口护理在真实临床实践中对糖尿病足溃疡的比较:德国 DiaFu-RCT 的结果。
BMJ Open. 2020 Mar 24;10(3):e026345. doi: 10.1136/bmjopen-2018-026345.
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Stem cell therapy for chronic skin wounds in the era of personalized medicine: From bench to bedside.个性化医疗时代慢性皮肤伤口的干细胞疗法:从实验室到临床应用
Genes Dis. 2019 Sep 17;6(4):342-358. doi: 10.1016/j.gendis.2019.09.008. eCollection 2019 Dec.
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An open-label trial of cryopreserved human umbilical cord in the treatment of complex diabetic foot ulcers complicated by osteomyelitis.一项关于冷冻保存人脐带治疗伴有骨髓炎的复杂糖尿病足溃疡的开放性试验。
Wound Repair Regen. 2019 Nov;27(6):680-686. doi: 10.1111/wrr.12754. Epub 2019 Aug 19.
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Platelet Rich Plasma: New Insights for Cutaneous Wound Healing Management.富血小板血浆:皮肤伤口愈合管理的新见解
J Funct Biomater. 2018 Jan 18;9(1):10. doi: 10.3390/jfb9010010.
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