Ocular Surface Center, Miami, FL 33173, USA.
Cornea. 2010 Dec;29(12):1386-91. doi: 10.1097/ICO.0b013e3181e2eac5.
To report Demodex infestation in pediatric blepharoconjunctivitis.
A retrospective review of 12 patients, with ages from 2.5-11 years, with chronic blepharoconjunctivitis who failed to respond to conventional treatments. Demodex was detected by lash sampling and microscopic examination. Patients were treated with 50% tea tree oil (TTO) eyelid scrubs or 5% TTO ointment eyelid massages for 4-6 weeks.
Demodex mites were found in all, but 1 case had cylindrical dandruff in the lashes. After 1 week of TTO treatment, all patients showed dramatic resolution of ocular irritation and inflammation while Demodex counts dropped. All corneal signs resolved within 2 weeks except for a residual anterior stromal scar in 1 eye. During a follow-up period of 8.3 ± 4.6 months, 1 patient showed recurrent inflammation, which was successfully managed by a second round of TTO treatment.
Demodicosis should be considered as a potential cause of pediatric refractory blepharoconjunctivitis. Eyelid scrubs or massage with TTO could be an effective treatment regimen in these cases.
报告小儿睑结膜炎中的螨虫感染。
回顾性分析了 12 例年龄在 2.5-11 岁之间的慢性睑结膜炎患者,这些患者对常规治疗反应不佳。通过睫毛取样和显微镜检查来检测螨虫。患者接受 50%茶树油(TTO)眼睑擦洗或 5%TTO 眼膏眼睑按摩治疗 4-6 周。
除 1 例外,所有患者的睫毛中均发现螨虫,但该例有圆柱状头皮屑。在 TTO 治疗 1 周后,所有患者的眼部刺激和炎症均明显缓解,螨虫数量下降。所有角膜体征均在 2 周内消退,除 1 眼遗留前基质瘢痕。在 8.3±4.6 个月的随访期间,1 例患者出现复发性炎症,通过第二轮 TTO 治疗成功控制。
螨虫感染应被视为小儿难治性睑结膜炎的潜在病因。在这些病例中,TTO 眼睑擦洗或按摩可能是一种有效的治疗方案。