The Department of Ophthalmology and Visual Neuroscience, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
Graefes Arch Clin Exp Ophthalmol. 2011 Mar;249(3):369-76. doi: 10.1007/s00417-010-1506-7. Epub 2010 Sep 17.
To evaluate the efficacy and safety of 25-gauge transconjunctival sutureless vitrectomy (25-G TSV) in the management of vitreoretinal complications of proliferative diabetic retinopathy (PDR).
A retrospective review of a noncomparative interventional case series including 200 eyes of 164 consecutive patients who underwent 25-G TSV for the management of PDR was performed. The main outcome measures were preoperative and postoperative visual acuity and intraocular pressure (IOP), the surgical success rate, and intraoperative and postoperative complications. All cases had a follow-up period of at least 6 months.
The mean logarithm of the minimum angle of resolution (LogMAR) visual acuity was significantly improved from 1.55 preoperatively to 0.72 at the final visit. No intraoperative complications related to the 25-G TSV procedure were recorded. Transient hypotony was recorded in 18 eyes (9%) on postoperative day 1 and 15 eyes (7.5%) on postoperative day 5. Two of these eyes (1%) had choroidal detachment on postoperative day 5. One case showed bacterial endophthalmitis after the second surgery. The single operation and final surgical success rates were 81.5% and 98% respectively.
These outcomes of 25-G TSV showed its safety and efficacy in the management of PDR.
评估 25G 经结膜无缝线玻璃体切除术（25-G TSV）治疗增生性糖尿病视网膜病变（PDR）的玻璃体视网膜并发症的疗效和安全性。
回顾性分析了 164 例连续患者的 200 只眼的非对照干预性病例系列研究，这些患者均因 PDR 接受了 25-G TSV 治疗。主要观察指标为术前和术后视力及眼压（IOP）、手术成功率及术中、术后并发症。所有病例的随访时间至少为 6 个月。
平均最小分辨角对数（LogMAR）视力从术前的 1.55 显著提高到最终随访时的 0.72。未记录到与 25-G TSV 手术相关的术中并发症。术后第 1 天 18 只眼（9%）和第 5 天 15 只眼（7.5%）出现一过性低眼压。其中 2 只眼（1%）在术后第 5 天出现脉络膜脱离。1 例在第二次手术后出现细菌性眼内炎。单次手术和最终手术成功率分别为 81.5%和 98%。
25-G TSV 的这些结果表明其在治疗 PDR 方面是安全有效的。
Zotero 插件