Department of Ophthalmology, Gachon University Gil Hospital, Incheon, Korea.
Retina. 2012 Oct;32(9):1767-74. doi: 10.1097/IAE.0b013e3182475ad6.
To compare rates of early postoperative hypotony and intraocular pressure (IOP) elevation between 23-gauge sutureless vitrectomies with and without phacoemulsification and intraocular lens implantation in patients with proliferative diabetic retinopathy.
This study reviewed the medical records of 302 eyes of patients who underwent primary 23-gauge sutureless vitrectomy for the complications of proliferative diabetic retinopathy. A case series of 207 eyes that underwent combined vitrectomy and cataract surgery (combined group) was compared with that of 95 eyes that underwent vitrectomy only (vitrectomy group): The eyes that remained phakic after the vitrectomy were excluded from this study. The main outcome measures were postoperative hypotony (IOP < 6 mmHg or IOP < 10 mmHg with choroidal detachment) and IOP elevation (>30 mmHg).
Postoperative hypotony was identified in 4 (1.9%) of 207 eyes in combined group, but in 7 (7.4%) of 95 eyes in vitrectomy group (P = 0.048). Rate of IOP elevation was very low and not different between the two groups. The multivariate analysis showed that vitrectomy without cataract surgery was associated with the postoperative hypotony (odds ratio = 4.6, P = 0.045).
The incidence of early postoperative hypotony was lower in combined sutureless vitrectomy and cataract surgery than in sutureless vitrectomy alone and that of IOP elevation was very low in both groups. The maintenance of a stable IOP with a low risk of IOP fluctuation may be an additional advantage of sutureless diabetic vitrectomy combined with cataract surgery.
比较伴有或不伴有白内障超声乳化及人工晶状体植入的 23 G 无缝线玻璃体切除术治疗增生性糖尿病视网膜病变患者术后早期低眼压和眼压升高的发生率。
本研究回顾性分析了 302 例因增生性糖尿病视网膜病变并发症行初次 23G 无缝线玻璃体切除术患者的病历。将 207 例联合玻璃体切割术和白内障手术(联合组)的病例系列与 95 例仅行玻璃体切割术(玻璃体切割组)的病例系列进行比较:排除了玻璃体切割术后仍为白内障的患者。主要观察指标为术后低眼压(眼压<6mmHg 或伴脉络膜脱离的眼压<10mmHg)和眼压升高(>30mmHg)。
联合组 207 只眼中有 4 只(1.9%)发生术后低眼压,而玻璃体切割组 95 只眼中有 7 只(7.4%)发生术后低眼压(P=0.048)。两组之间眼压升高的发生率都很低且无差异。多变量分析显示,不伴白内障手术的玻璃体切除术与术后低眼压相关(比值比=4.6,P=0.045)。
联合无缝线玻璃体切割术和白内障手术治疗的患者术后早期低眼压的发生率低于单纯无缝线玻璃体切除术治疗的患者,两组的眼压升高发生率均较低。与单纯无缝线糖尿病玻璃体切除术相比,联合白内障手术的稳定眼压和低眼压波动风险可能是其另一个优势。