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[阿戈美拉汀治疗期间的QTc间期延长]

[QTc prolongation during treatment with agomelatine].

作者信息

Kozian Ralf, Syrbe Günther

机构信息

Asklepiosklinik Stadtroda, Stadtroda.

出版信息

Psychiatr Prax. 2010 Nov;37(8):405-7. doi: 10.1055/s-0030-1248578. Epub 2010 Sep 16.

DOI:10.1055/s-0030-1248578
PMID:20848378
Abstract

A 58 years old woman with a depression showed a QTc prolongation during treatment with agomelatine which was fully reversible after stopping administration. QTc prolongation during antidepressant treatment is not unknown especially when tricyclic antidepressants are administered. This case is the first occurrence of a QTc prolongation during treatment with agomelatine.

摘要

一名58岁患有抑郁症的女性在接受阿戈美拉汀治疗期间出现QTc延长，停药后完全可逆。抗抑郁治疗期间出现QTc延长并非罕见，尤其是在使用三环类抗抑郁药时。该病例是阿戈美拉汀治疗期间首次出现QTc延长。

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