Department of Otorhinolaryngology-Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.
Head Neck. 2010 Dec;32(12):1635-40. doi: 10.1002/hed.21382.
Our aim was to evaluate the diagnostic accuracy of fine-needle aspiration cytology (FNAC) for Warthin tumors of the parotid gland.
All cytologic diagnoses of Warthin tumor between 1990 and 2007 were correlated with available histology. In addition, our results were compared to current literature.
In 310 cases, Warthin tumor was diagnosed by FNAC. In 133 cases, (43%) both cytology and histology were available. In 127 of these 133 cases (95.5%), the diagnosis Warthin tumor was confirmed by histology. In 4 cases (3%), a benign lesion was diagnosed and 2 (1.5%) revealed a malignant lesion. On review, those cytologic diagnoses were not certain. In the literature, 11 missed malignancies (5.4%) in 202 cases were reported.
The diagnostic accuracy of FNAC for the diagnosis of Warthin tumor is high and the percentage of missed malignant tumors is very low. Our results imply that a cytologic diagnosis of Warthin tumor may justify conservative treatment.
我们旨在评估细针吸取细胞学（FNAC）对腮腺沃辛瘤的诊断准确性。
将 1990 年至 2007 年间所有的沃辛瘤细胞学诊断与可用的组织学进行相关分析。此外，我们的结果与当前文献进行了比较。
在 310 例病例中，FNAC 诊断为沃辛瘤。在 133 例病例中（43%），细胞学和组织学均可用。在这 133 例中的 127 例（95.5%），组织学证实了沃辛瘤的诊断。在 4 例（3%）中，诊断为良性病变，2 例（1.5%）显示恶性病变。回顾性分析，这些细胞学诊断并不确定。在文献中，202 例中报告了 11 例恶性肿瘤漏诊（5.4%）。
FNAC 对沃辛瘤的诊断准确性较高，漏诊恶性肿瘤的比例非常低。我们的结果表明，细胞学诊断为沃辛瘤可能可以支持保守治疗。
