Department of Psychology, University of California, San Diego, La Jolla, California 92093, USA.
Hippocampus. 2010 Nov;20(11):1195-205. doi: 10.1002/hipo.20854.
Many recent studies have investigated how the structures of the medial temporal lobe (MTL) support recollection and familiarity, which are two processes widely thought to support recognition memory. The behavioral methods that are used to isolate recollection and familiarity in neuroimaging and lesion studies typically assume that recollection is a categorical process and not a continuous process. A categorical process is one that either occurs or does not occur for a particular test item (yielding high confidence and high accuracy when it does occur), whereas a continuous process is one that comes in degrees (yielding varying degrees of confidence and accuracy). Studies suggesting that the hippocampus selectively supports the recollection process (such as those that use the Remember/Know procedure or rely on Receiver Operating Characteristic analysis) generally depend on the categorical view of recollection, but much recent evidence suggests that recollection is a continuous process. If recollection is a continuous process (i.e., if recollection comes in degrees), then evidence that has been taken to mean that the hippocampus selectively supports recollection is also compatible with the idea that the hippocampus supports both recollection and familiarity. We suggest that an alternative method can be used to effectively investigate recollection and familiarity in the MTL, one that is valid whether recollection is a categorical or a continuous process.
许多最近的研究调查了内侧颞叶(MTL)的结构如何支持回忆和熟悉度,这两个过程被广泛认为支持识别记忆。在神经影像学和病变研究中用于分离回忆和熟悉度的行为方法通常假定回忆是一个分类过程,而不是一个连续的过程。分类过程是指对于特定的测试项目要么发生要么不发生(当它发生时会产生高置信度和高准确性),而连续过程则是按程度发生的(产生不同程度的置信度和准确性)。一些研究表明海马体选择性地支持回忆过程(例如使用“记得/知道”程序或依赖于接收者操作特征分析的研究),这些研究通常依赖于回忆的分类观点,但最近有很多证据表明回忆是一个连续的过程。如果回忆是一个连续的过程(即,如果回忆有程度之分),那么那些被认为表明海马体选择性地支持回忆的证据也与海马体支持回忆和熟悉度的观点是一致的。我们建议,可以使用一种替代方法来有效地研究 MTL 中的回忆和熟悉度,无论回忆是分类过程还是连续过程,这种方法都是有效的。