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[下肢血管血栓闭塞性脉管炎和动脉硬化闭塞症的形态学标准]

[The morphological criteria of thromboangiitis and arteriosclerosis obliterans of the vessels of the lower extremities].

作者信息

Iarygin N E, Shilkina N P, Romanov V A, Lileeva M A

出版信息

Ter Arkh. 1990;62(10):122-5.

PMID:2084874
Abstract

The differences in pathology of the leg and foot arteries are described in patients with thromboangiitis obliterans (60 cases) and atherosclerosis (30 cases). Based on the operative and biopsy material it has been shown that thromboangiitis obliterans is associated with immune inflammation of the arteries, manifesting itself by productive or, more rarely, by necrotic arteritis. In the latter condition, the wall of the impaired vessels contains immune complexes. In patients with atherosclerosis, the muscular type arteries of the legs and feet show dystrophic and fibroblastic lesions seen primarily in the intima and manifesting themselves by the enlargement of its connective tissue. No immune complexes were discovered in the wall of such arteries.

摘要

本文描述了60例血栓闭塞性脉管炎患者和30例动脉粥样硬化患者下肢和足部动脉的病理学差异。根据手术和活检材料显示,血栓闭塞性脉管炎与动脉的免疫炎症相关,表现为增殖性动脉炎,较少见的为坏死性动脉炎。在后一种情况下,受损血管壁含有免疫复合物。在动脉粥样硬化患者中,下肢和足部的肌型动脉出现营养不良性和成纤维细胞性病变,主要见于内膜,并表现为结缔组织增生。在这些动脉壁中未发现免疫复合物。

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