Horimoto Taisuke, Yamada Shinya, Kawaoka Yoshihiro
Division of Virology, Institute of Medical Science, University of Tokyo.
Uirusu. 2010 Jun;60(1):3-8. doi: 10.2222/jsv.60.3.
In the spring of 2009, a novel swine-origin H1N1 virus, whose antigenicity is quite different from those of seasonal human H1N1 strains, emerged in Mexico and readily transmitted and spread among humans, resulting in the first influenza pandemic in the 21st century. This novel H1N1 virus was shown to be a triple reassortant comprising genes derived from avian, human, and swine viruses. Here, we review our current knowledge of this pandemic influenza virus and discuss future aspects of the pandemic.
2009年春,一种新型猪源H1N1病毒在墨西哥出现,其抗原性与季节性人类H1N1毒株截然不同,并迅速在人群中传播扩散,引发了21世纪的首次流感大流行。这种新型H1N1病毒被证明是一种三重重组病毒,包含来自禽类、人类和猪病毒的基因。在此,我们回顾了目前对这种大流行性流感病毒的认识,并讨论了该大流行的未来发展情况。