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妊娠期急性和慢性肺炎衣原体感染并发子痫前期。

Acute and chronic Chlamydia pneumoniae infection in pregnancy complicated with preeclampsia.

作者信息

Chrisoulidou Alexandra, Goulis Dimitrios G, Iliadou Paschalia K, Dave Jitendra R, Bili Helen, Simms Carol, Redman Christopher W G, Williamson Catherine

机构信息

Unit of Endocrinology and Endocrine Oncology, Theagenio Hospital, Thessaloniki, Greece.

出版信息

Hypertens Pregnancy. 2011;30(2):164-8. doi: 10.3109/10641955.2010.506235. Epub 2010 Sep 17.

Abstract

OBJECTIVE

To investigate whether Chlamydia pneumoniae (Cp) infection is more common in women whose current pregnancy is complicated with preeclampsia (PE) as compared to pregnant women without PE.

METHODS

Thirty pregnant women with PE and 30 pregnant women without PE were studied between 29 and 30 weeks of gestation. The presence of an acute or chronic Cp infection was determined by the estimations of serum IgG, IgM, and IgA Cp antibodies.

RESULTS

None of the women were diagnosed as having acute Cp infection. Prevalence of chronic Cp infection was 53 and 66% in the PE and control groups, respectively (X(2), p = 0.068).

CONCLUSION

Chronic Cp infection is not more common in women whose pregnancy is complicated with PE as compared to pregnant women without PE. Therefore, no association between Cp infection and PE can be established.

摘要

目的

调查与未患子痫前期(PE)的孕妇相比,当前妊娠合并子痫前期的女性衣原体肺炎(Cp)感染是否更常见。

方法

在妊娠29至30周期间,对30例患子痫前期的孕妇和30例未患子痫前期的孕妇进行研究。通过检测血清IgG、IgM和IgA Cp抗体来确定是否存在急性或慢性Cp感染。

结果

所有女性均未被诊断为急性Cp感染。慢性Cp感染在PE组和对照组中的患病率分别为53%和66%(X(2),p = 0.068)。

结论

与未患子痫前期的孕妇相比,妊娠合并子痫前期的女性慢性Cp感染并不更常见。因此,无法确定Cp感染与子痫前期之间存在关联。

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