Doffoel-Hantz Valérie, Robert Pierre-Yves, Bédane Christophe
CHU Dupuytren, centre de référence des maladies bulleuses auto-immunes, service de dermatologie, 87042 Limoges, France.
Presse Med. 2010 Oct;39(10):1049-57. doi: 10.1016/j.lpm.2010.07.001. Epub 2010 Sep 17.
Mucous membrane pemphigoid belongs to the family of sub-epidermal bullous diseases and is clinically characterized by mucosal involvement leading to fibrosis and scarring. Cutaneous involvement is unfrequent and oral mucosa and conjunctivas are the most frequently involves mucosa. Treatment relies on anti-inflammatory and immunosuppressive drugs. The main goal is the limitation of the fibrosing potential of the autoimmune deposits within various mucous membranes.
黏膜类天疱疮属于表皮下大疱性疾病家族,临床特征为黏膜受累导致纤维化和瘢痕形成。皮肤受累不常见,口腔黏膜和结膜是最常受累的黏膜。治疗依赖抗炎和免疫抑制药物。主要目标是限制各种黏膜内自身免疫沉积物的纤维化潜能。