Department of Oral Pathology and Medicine, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
J Endod. 2010 Oct;36(10):1707-11. doi: 10.1016/j.joen.2010.06.015. Epub 2010 Aug 11.
The lateral periodontal cyst is an uncommon odontogenic developmental lesion and chiefly arises in the alveolar bone between the roots of a pair of erupted teeth or lateral to a tooth root. Two atypical cases of the lateral periodontal cyst occurring in periapical sites are reported.
Both lesions presented as an incidental radiographic finding, appearing as an apical radiolucency with well-circumscribed sclerotic borders. One lesion, initially suspected to be of pulpal origin, persisted after endodontic therapy; the other case was first considered to be an odontogenic keratocyst. A biopsy was performed on each patient for lesional identity.
Histopathologic assessment of each lesion was consistent with a lateral periodontal cyst and revealed thin, nonkeratinized epithelial linings containing nodular plaques and clear cells. The cyst walls were thickened and had minimal inflammation.
The featured cases show that the lateral periodontal cyst is not always confined to the interradicular region and can masquerade as a lesion of endodontic origin. Aberrant cases warrant long-term surveillance.
牙周旁囊肿是一种不常见的牙源性发育性病变，主要发生在一对已萌出牙的牙根之间的牙槽骨中，或在牙根的外侧。报告了两个发生在根尖部位的不典型牙周旁囊肿病例。
两个病变均为偶然的影像学发现，表现为边界清晰的根尖透光区伴硬化。一个病变最初怀疑为牙髓来源，在根管治疗后仍存在；另一个病例最初被认为是牙源性角化囊肿。对每位患者进行活检以确定病变性质。
每个病变的组织病理学评估均符合牙周旁囊肿，显示薄的、非角化的上皮衬里，其中含有结节状斑块和透明细胞。囊肿壁增厚，炎症轻微。
这些特征性病例表明，牙周旁囊肿并不总是局限于根间区域，也可能表现为牙髓来源的病变。异常病例需要长期监测。
