Imaizumi Y, Asaka A, Inouye E
Institute of Population Problems, Ministry of Health and Welfare, Tokyo, Japan.
Acta Genet Med Gemellol (Roma). 1990;39(3):345-50. doi: 10.1017/s0001566000005262.
Source of data is "Survey on Socio-Economic Aspects of Vital Events-Plural Births in 1975", including 12,392 twin pairs, 124 triplet sets, 7 quadruplet sets and 1 quintuplet set. Fetal deaths were 3,285 for twins, 141 for triplets, 17 for quadruplets, and 5 for quintuplets, among which the number of birth defects were 78, 3, 0, and 0 respectively. Concordant twin pairs with the same category of birth defect were 20 among 56 pairs (0.36). As for the remaining 36 pairs, 2 pairs had different category of birth defects, 27 pairs had liveborn cotwins, and 7 pairs were both fetal deaths among which a twin had birth defect. The second-born twins had birth defects more frequently than the first-born twins among fetal deaths (28 vs 6).
数据来源是“1975年多胞胎生命事件的社会经济方面调查”，包括12392对双胞胎、124组三胞胎、7组四胞胎和1组五胞胎。双胞胎的胎儿死亡数为3285例，三胞胎为141例，四胞胎为17例，五胞胎为5例，其中出生缺陷数分别为78例、3例、0例和0例。在56对同类别出生缺陷的一致双胞胎中，有20对（0.36）。其余36对中，2对有不同类别的出生缺陷，27对有存活的双生子，7对均为胎儿死亡，其中一对双胞胎有出生缺陷。在胎儿死亡中，第二出生的双胞胎比第一出生的双胞胎更频繁出现出生缺陷（28例对6例）。
