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中国辅助生殖技术后出生缺陷：7 个中心 15405 例子代分析（2004-2008 年）。

Birth defects after assisted reproductive technologies in China: analysis of 15,405 offspring in seven centers (2004 to 2008).

机构信息

Center for Reproductive Medicine, Shandong University, Jinan, People's Republic of China.

出版信息

Fertil Steril. 2011 Jan;95(1):458-60. doi: 10.1016/j.fertnstert.2010.08.024. Epub 2010 Sep 20.

DOI:10.1016/j.fertnstert.2010.08.024
PMID:20850722
Abstract

This first large-scale report of birth defects in 15,405 offspring conceived by assisted reproductive technologies in China found infants born after IVF alone to have a birth defect frequency comparable to that in the general Chinese population; rates were nonsignificantly higher in infants conceived with use of intracytoplasmic sperm injection compared with those conceived after IVF alone.

摘要

这是中国首例关于 15405 例通过辅助生殖技术出生的缺陷儿的大规模报告，研究发现，单独采用体外受精技术（IVF）出生的婴儿缺陷发生率与中国一般人群相当；与单独 IVF 相比，采用胞浆内单精子注射（ICSI）技术受孕的婴儿缺陷率略高，但差异无统计学意义。

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Fertil Steril. 2011 Jan;95(1):458-60. doi: 10.1016/j.fertnstert.2010.08.024. Epub 2010 Sep 20.
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