Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
J Thorac Cardiovasc Surg. 2010 Nov;140(5):1104-9. doi: 10.1016/j.jtcvs.2010.08.013. Epub 2010 Sep 20.
Few studies have described the survival of low-birth-weight infants weighing less than 1.5 kg at operation for a cardiac malformation. Our goal was to determine if body weight at surgery affects survival.
This was a retrospective cohort study using outcome data from the Pediatric Cardiac Care Consortium between 1982 and 2006.
We reviewed the outcomes of 450 consecutive infants with a cardiac anomaly and a birth weight of less than 1.5 kg, and weight of less than 2.5 kg at surgery. Of these, 179 patients had undergone surgery with a weight of less than 1.5 kg and 271 patients weighed 1.5 to 2.5 kg at surgery. The 30-day survival rate was 83% for cohort 1 and 86% for cohort 2. For patients not requiring cardiopulmonary bypass, the 30-day survival rate was 86% for cohort 1 and 92% for cohort 2. For patients requiring cardiopulmonary bypass, the 30-day survival rate was 69% for cohort 1 and 73% for cohort 2. No notable improvement in the outcomes occurred over time.
For low-birth-weight infants (weight < 1.5 kg) undergoing a major cardiac procedure, the survival of infants weighing less than 1.5 kg at surgery is comparable to that of infants who weighed 1.5 to 2.5 kg. We conclude that, in our series, weight was not an independent risk factor for mortality, and, therefore, operative delay because of patient weight might be unwarranted.
很少有研究描述体重低于 1.5 公斤的心脏畸形患儿在手术时的生存情况。我们的目的是确定手术时的体重是否影响生存。
这是一项回顾性队列研究，使用了 1982 年至 2006 年期间小儿心脏护理联盟的结果数据。
我们回顾了 450 例体重低于 1.5 公斤且手术时体重低于 2.5 公斤的心脏畸形婴儿的结局，其中 179 例体重低于 1.5 公斤接受了手术，271 例体重为 1.5 至 2.5 公斤。第 1 组的 30 天生存率为 83%，第 2 组为 86%。对于不需要体外循环的患者，第 1 组的 30 天生存率为 86%，第 2 组为 92%。对于需要体外循环的患者，第 1 组的 30 天生存率为 69%，第 2 组为 73%。随着时间的推移，结果没有明显改善。
对于接受重大心脏手术的低出生体重儿（体重 < 1.5 公斤），手术时体重低于 1.5 公斤的婴儿的生存率与体重为 1.5 至 2.5 公斤的婴儿相当。我们得出的结论是，在我们的系列中，体重不是死亡的独立危险因素，因此，因为患者体重而延迟手术可能是不必要的。
