Department of Urology, Maastricht University Medical Centre, Maastricht, the Netherlands.
J Urol. 2010 Nov;184(5):1997-2000. doi: 10.1016/j.juro.2010.06.142. Epub 2010 Sep 18.
We present long-term followup data on the outcome of sacral neuromodulation using the tined lead procedure.
We conducted a single center study including all patients who received an implantable neurostimulator between 2002 and 2005 using the tined lead technique. Treatment efficacy was evaluated by comparing the data of a 3-day voiding diary filled out in May 2009 to the data before the onset of sacral neuromodulation treatment (baseline). Clinical success was defined as more than 50% improvement in at least 1 of the relevant voiding diary parameters.
A total of 64 patients underwent implantation with an implantable neurostimulator using the tined lead procedure. Mean followup was 53 months (range 35 to 77). Five patients died of causes unrelated to sacral neuromodulation and they were not included in analysis. The implantable neurostimulator was removed from 7 patients and 3 stopped using the neurostimulator. Voiding diary analysis showed that 38 of 59 patients (64%) were successfully treated. There were 21 patients (33%) who underwent a surgical revision due to an adverse event and 1 (1.6%) who underwent lead revision because of suspected lead migration.
Sacral neuromodulation with the tined lead procedure is a safe and effective treatment for patients with overactive bladder symptoms or urinary retention.
我们介绍使用叉状电极的骶神经调节治疗的长期随访结果。
我们进行了一项单中心研究，纳入了 2002 年至 2005 年间使用叉状电极技术植入可植入神经刺激器的所有患者。通过比较 2009 年 5 月填写的 3 天排尿日记数据与骶神经调节治疗开始前（基线）的数据，评估治疗效果。临床成功定义为至少 1 项相关排尿日记参数改善超过 50%。
共有 64 例患者接受了使用叉状电极的可植入神经刺激器植入术。平均随访时间为 53 个月（范围 35 至 77 个月）。5 例患者因与骶神经调节无关的原因死亡，未纳入分析。7 例患者因不良事件移除了可植入神经刺激器，3 例患者停止使用神经刺激器。排尿日记分析显示，59 例患者中的 38 例（64%）得到了有效治疗。21 例（33%）患者因不良事件行手术修正，1 例（1.6%）因疑似电极移位行电极修正。
使用叉状电极的骶神经调节是治疗膀胱过度活动症或尿潴留患者的安全有效方法。
