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先天性腮腺炎肺炎:新生儿呼吸窘迫的罕见病因。

Congenital mumps pneumonia: a rare cause of neonatal respiratory distress.

作者信息

Groenendaal F, Rothbarth P H, van den Anker J N, Spritzer R

机构信息

Department of Paediatrics, Academic Hospital Rotterdam/Sophia Children's Hospital, Rotterdam, The Netherlands.

出版信息

Acta Paediatr Scand. 1990 Dec;79(12):1252-4. doi: 10.1111/j.1651-2227.1990.tb11421.x.

Abstract

A case of a fullterm infant with severe neonatal respiratory distress due to mumps infection is reported. Pregnancy was complicated by a self-limited febrile illness of the mother about two weeks before birth. Foetal heart rate patterns and delivery were normal. Immediately after birth the infant needed mechanical ventilation. Bacterial infections, as well as congenital cardiac or pulmonary malformations were excluded. The infant showed serologic evidence of mumps infection: IgM antibodies to mumps virus were highly positive. He expired on the 9th day of life due to bilateral pneumothoraces and pneumopericardium. Post-mortem examination showed interstitial pneumonia with intra-alveolar multinucleated giant cells, suggesting viral disease. This case demonstrates, that mumps pneumonia should be included in the differential diagnosis of severe neonatal respiratory distress in fullterm neonates.

摘要

报告了一例因腮腺炎感染导致足月新生儿严重呼吸窘迫的病例。母亲在分娩前约两周患了一种自限性发热疾病,使孕期复杂化。胎儿心率模式和分娩过程正常。婴儿出生后立即需要机械通气。排除了细菌感染以及先天性心脏或肺部畸形。婴儿有腮腺炎感染的血清学证据:腮腺炎病毒IgM抗体呈强阳性。婴儿在出生后第9天因双侧气胸和心包积气死亡。尸检显示间质性肺炎伴肺泡内多核巨细胞,提示为病毒性疾病。该病例表明,腮腺炎肺炎应纳入足月新生儿严重呼吸窘迫的鉴别诊断中。

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