在乳酸乳球菌中 sortase A 的功能。
Functionality of sortase A in Lactococcus lactis.
机构信息
INRA, UMR1319 Micalis, Domaine de Vilvert, F-78352 Jouy-en-Josas, France.
出版信息
Appl Environ Microbiol. 2010 Nov;76(21):7332-7. doi: 10.1128/AEM.00928-10. Epub 2010 Sep 17.
Abstract
Lactococcus lactis IL1403 harbors a putative sortase A (SrtA) and 11 putative sortase substrates that carry the canonical LPXTG signature of such substrates. We report here on the functionality of SrtA to anchor five LPXTG substrates to the cell wall, thus suggesting that SrtA is the housekeeping sortase in L. lactis IL1403.
摘要
乳球菌 IL1403 含有一个假定的天冬酰胺酰内肽酶 A（SrtA）和 11 个假定的天冬酰胺酰内肽酶底物，这些底物带有此类底物的典型 LPXTG 特征。我们在此报告 SrtA 将五个 LPXTG 底物锚定到细胞壁上的功能，这表明 SrtA 是乳球菌 IL1403 中的管家天冬酰胺酰内肽酶。
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