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[米拉佐工业区(西西里岛)附近居民的死亡率和发病率队列研究]

[Mortality and morbidity cohort study of residents in the neighbourhood of Milazzo industrial area (Sicily)].

作者信息

Fazzo Lucia, Puglisi Francesca, Pellegrino Angela, Fiumanò Giovanna, Mudu Pierpaolo, Bruno Caterina, Andaloro Pasquale, Cernigliaro Achille, Comba Pietro

机构信息

Dipartimento di ambiente e connessa prevenzione primaria, Istituto superiore di sanità, Viale Regina Elena 299, 00161, Roma.

出版信息

Epidemiol Prev. 2010 May-Jun;34(3):80-6.

Abstract

OBJECTIVE

The municipality of Pace del Mela, together with Milazzo and San Filippo del Mela, has been recognized as a contaminated site of national concern. The purpose of the present study is to evaluate the health status of subjects resident in the Gabbia district, which is close to the industrial areas of both, Pace del Mela and Milazzo.

SETTING AND PARTICIPANTS

All streets and addresses of the area of interest have been identified, taking into account their changes in name over time. The cohort of subjects who lived in the area for any period of time from September 1st, 1984, through December 31st, 2007 has been reconstructed by manual consultation of the Registrar Office files. Standardized mortality ratios, specific for cause, age class, gender and calendar period, have been computed using as reference the Sicilian population. Standardised incidence ratios, based on regional hospital discharge files, have been computed for the years 2001-2007. The cohort is constituted by 457 subjects, 230 men and 227 women. Ascertainment of vital status has not been possible for 39 subjects, corresponding to 8.5% of the cohort.

RESULTS

Observed mortality for all causes and for all cancers is consistent with expected figures (62 observed vs 63 expected and 14 observed vs 15 expected, respectively). Observed cancer morbidity is inferior to the corresponding expected figure (SIR=0.49, CI 95%: 0.31-0.79).

CONCLUSION

The health profile of the Gabbia district population, as estimated from mortality and hospital discharge records, does not show major departures from expected figures.

摘要

目的

帕切-德尔梅拉市与米拉佐市和圣菲利波-德尔梅拉市一起,已被认定为受国家关注的污染场地。本研究的目的是评估居住在加比亚区的居民的健康状况,该地区靠近帕切-德尔梅拉市和米拉佐市的工业区。

背景与参与者

考虑到该地区街道和地址随时间的名称变化,已确定了所有感兴趣区域的街道和地址。通过手动查阅户籍办公室档案,重建了1984年9月1日至2007年12月31日期间在该地区居住过任何时间段的受试者队列。以西西里岛人口为参照,计算了按病因、年龄组、性别和日历期分类的标准化死亡率。根据地区医院出院档案,计算了2001 - 2007年的标准化发病率。该队列由457名受试者组成,其中男性230名,女性227名。39名受试者的生命状态无法确定,占队列的8.5%。

结果

所有原因和所有癌症的观察到的死亡率与预期数字一致(分别为62例观察到的死亡与63例预期死亡,以及14例观察到患癌死亡与15例预期患癌死亡)。观察到的癌症发病率低于相应的预期数字(标准化发病比=0.49,95%置信区间:0.31 - 0.79)。

结论

根据死亡率和医院出院记录估计,加比亚区居民的健康状况与预期数字没有重大偏差。

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