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输精管复通术与精子提取的试管婴儿:哪个更好?

Vasectomy reversal versus IVF with sperm retrieval: which is better?

机构信息

Department of Urology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

出版信息

Curr Opin Urol. 2010 Nov;20(6):503-9. doi: 10.1097/MOU.0b013e32833f1b35.

Abstract

PURPOSE OF REVIEW

This paper will describe why this review is timely and relevant. Over the past two decades, treatment options for couples with reconstructible obstructive azoospermia have improved tremendously. Advances in assisted reproductive technologies (ART), specifically sperm retrieval techniques for intracytoplasmic sperm injection coupled with in-vitro fertilization, as well as refinements in microsurgical reconstruction have led to improved outcomes and cost-effectiveness. Providing the most up-to-date care based on the most recent data allows for better patient outcomes and satisfaction.

RECENT FINDINGS

Microsurgical reconstruction of the vas has remained a cost-effective, reliable and effective means of restoring fertility in the majority of men who have previously undergone vasectomy when the reconstruction is performed by an experienced microsurgeon. However, there are specific instances in which sperm retrieval/IVF/ICSI may be a more appropriate treatment modality as ART techniques continue to improve.

SUMMARY

Data comparing surgical reconstruction versus sperm retrieval/ICSI/IVF are neither randomized nor homogenous. Therefore, a comprehensive understanding of the factors that can affect outcomes, overall cost, and the morbidity associated with each treatment modality, respective of the institution providing the treatment, is strongly recommended.

摘要

目的综述

本文将阐述为何该综述具有及时性和相关性。在过去的二十年中,可重建性梗阻性无精子症夫妇的治疗选择有了极大的改善。辅助生殖技术(ART)的进步,特别是用于胞浆内精子注射的精子获取技术与体外受精相结合,以及显微外科重建技术的改进,导致了更好的结果和成本效益。基于最新数据提供最新的护理可以改善患者的结果和满意度。

最近的发现

当由经验丰富的显微外科医生进行手术时,对先前接受过输精管切除术的大多数男性进行显微外科输精管重建仍然是一种具有成本效益、可靠且有效的恢复生育能力的方法。然而,在某些特定情况下,随着 ART 技术的不断改进,精子获取/IVF/ICSI 可能是更合适的治疗方法。

总结

比较手术重建与精子获取/ICSI/IVF 的数据既不是随机的,也不是同质的。因此,强烈建议全面了解可能影响结果、总费用以及与每种治疗方法相关的发病率的因素,分别考虑提供治疗的机构。

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