Department of Medical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, 310003 Hangzhou, Zhejiang, China.
Med Oncol. 2011 Dec;28 Suppl 1:S388-91. doi: 10.1007/s12032-010-9680-3. Epub 2010 Sep 18.
Primitive neuroectodermal tumor (PNET) arising in the urinary bladder is extremely rare. Here, we report a case of primary PNET of the urinary bladder in an aged Asian man that showed an aggressive clinical course. A 74-year-old man presented with frequency, dysuria, and gross hematuria. Pelvic computed tomography showed a mass in the urinary bladder. Microscopically, the tumor revealed sheets of uniform, small, round, blue cells, and immunohistochemical examination demonstrated primary PNET of the urinary bladder. Palliative chemotherapy was administered. After three courses of chemotherapy, his disease progressed and he died 4 months after diagnosis.
膀胱原始神经外胚层肿瘤（PNET）极为罕见。在此，我们报告一例老年亚洲男性膀胱原发性 PNET，其表现出侵袭性临床病程。一名 74 岁男性因尿频、尿痛和肉眼血尿就诊。盆腔计算机断层扫描显示膀胱内有一肿块。显微镜下，肿瘤显示为均匀的小而圆的蓝色细胞片，免疫组织化学检查显示为膀胱原发性 PNET。给予姑息性化疗。三个疗程化疗后，疾病进展，诊断后 4 个月死亡。
