钌催化的 1,6-环丙二烯炔和烯烃的串联开环/闭环/交叉复分解反应构建 3-吡咯啉骨架。
Ruthenium-catalyzed tandem ring-opening/ring-closing/cross-metathesis of 1,6-cyclopropene-ynes and olefins for the construction of the 3-pyrroline skeleton.
机构信息
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.
出版信息
Org Lett. 2010 Oct 15;12(20):4462-5. doi: 10.1021/ol101455c.
PMID:20853880
Abstract
Catalyzed by the first-generation Grubbs' ruthenium complex, tandem intramolecular/intermolecular metathesis of 1,6-enynes bearing a cyclopropene ring took place smoothly to produce 3-pyrroline derivatives in satisfactory yields via ring-opening/ring-closing/cross-metathesis processes.
摘要
在第一代 Grubbs 钌络合物的催化作用下，带有环丙烯环的 1,6-烯炔进行了串联的分子内/分子间复分解反应，通过开环/闭环/交叉复分解反应顺利地生成了 3-吡咯啉衍生物，产率令人满意。
Zotero 插件