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澳大利亚原住民儿童的下呼吸道感染

Lower respiratory infections in Australian Indigenous children.

作者信息

O'Grady Kerry-Ann F, Chang Anne B

机构信息

Child Health Division Centre for Clinical Research Excellence in Child and Adolescent Immunisation, Menzies School of Health Research, Charles Darwin University, Casuarina, Northern Territory, Australia.

出版信息

J Paediatr Child Health. 2010 Sep;46(9):461-5. doi: 10.1111/j.1440-1754.2010.01845.x.

Abstract

Despite Australia being one of the wealthiest countries of the world, Australian Indigenous children have a health status and social circumstance comparable to developing countries. Indigenous infants have 10 times the mortality rate for respiratory conditions. The lower respiratory infection (LRI) rate in Australian Indigenous children is at least as high as that of children in developing countries; the frequency of hospitalisations of Indigenous infants is triple that of non-Indigenous Australian infants (201.7 vs. 62.6/1000, respectively). While Indigenous Australian children have many risk factors for LRIs described in developing countries, there is little specific data, and hence, evidence-based intervention points are yet to be identified. Efficacy of conjugate vaccines for common bacterial causes of pneumonia has been less marked in Indigenous children than that documented overseas. Gaps in the management and prevention of disease are glaring. Given the burden of LRI in Indigenous children and the association with long-term respiratory dysfunction, LRIs should be addressed as a matter of priority.

摘要

尽管澳大利亚是世界上最富裕的国家之一,但澳大利亚原住民儿童的健康状况和社会环境却与发展中国家相当。原住民婴儿因呼吸道疾病的死亡率是其他儿童的10倍。澳大利亚原住民儿童的下呼吸道感染(LRI)率至少与发展中国家儿童一样高;原住民婴儿住院的频率是非原住民澳大利亚婴儿的三倍(分别为201.7例/1000人和62.6例/1000人)。虽然澳大利亚原住民儿童有许多在发展中国家所描述的导致下呼吸道感染的风险因素,但具体数据很少,因此,基于证据的干预点尚未确定。与海外记录的情况相比,结合疫苗对肺炎常见细菌病因的疗效在原住民儿童中不太明显。在疾病管理和预防方面的差距非常明显。鉴于原住民儿童下呼吸道感染的负担以及与长期呼吸功能障碍的关联,应将下呼吸道感染作为优先事项加以解决。

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