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偏头痛预防性治疗的临床决定因素:SMILE 观察性研究的贡献,该研究调查了法国初级保健偏头痛管理情况。

Clinical determinants of migraine preventive treatment: contribution of SMILE, an observational survey of primary care migraine management in France.

机构信息

Centre d'Urgences Céphalées, Lariboisière Hospital, Paris, France.

出版信息

Cephalalgia. 2010 Oct;30(10):1207-13. doi: 10.1177/0333102409355661. Epub 2010 Apr 23.

Abstract

METHODS

SMILE was an observational study carried out in France among office-based general practitioners (GPs) and neurologists from November 2005 to July 2006 to assess the determinants of prescription of migraine preventive therapy in primary care medicine. A total of 1467 GPs and 83 neurologists were included, treating 5417 and 248 migraine sufferers, respectively.

RESULTS

The main factors leading physicians to deem a patient eligible for preventive treatment were perceived medication overuse and frequency of headaches, and secondarily, severity of headaches and functional impact. On the other hand, patient satisfaction with the acute treatment of attacks and triptan use, and secondarily, a long migraine history were found to influence patient eligibility negatively.

DISCUSSION/CONCLUSION: Noticeably, psychiatric disorders (anxiety, stress) did not appear, aside from somatic factors, among the determinants that significantly influence physicians' judgment about the option of establishing a preventive treatment. However, they are important features of migraine condition and should be listed among the factors guiding choices about migraine preventive therapy.

摘要

方法

SMILE 是一项在法国开展的观察性研究,于 2005 年 11 月至 2006 年 7 月在坐诊的全科医生(GP)和神经科医生中进行,旨在评估初级保健医学中偏头痛预防治疗处方的决定因素。共纳入了 1467 名全科医生和 83 名神经科医生,分别治疗了 5417 名和 248 名偏头痛患者。

结果

促使医生认为患者适合预防性治疗的主要因素是感知到的药物滥用和头痛频率,其次是头痛的严重程度和功能影响。另一方面,患者对发作急性治疗的满意度和曲坦类药物的使用,其次是偏头痛病史较长,被发现对患者的资格有负面影响。

讨论/结论:值得注意的是,除了躯体因素外,精神障碍(焦虑、压力)并没有出现在影响医生对预防性治疗选择判断的决定因素中。然而,它们是偏头痛状况的重要特征,应该被列入偏头痛预防性治疗选择的指导因素中。

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