Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS, Brasil.
Arq Bras Cardiol. 2010 Oct;95(5):594-9. doi: 10.1590/s0066-782x2010005000128. Epub 2010 Sep 24.
[Corrected] Expiratory positive airway pressure (EPAP) is used in after cardiac surgeries. However, its hemodynamic effects have not been clearly studied.
To evaluate the hemodynamic changes caused by EPAP in patients after cardiac surgery monitored by Swan-Ganz.
Patients at the first or second cardiac surgery postoperative period hemodynamically stable with a Swan-Ganz catheter were included in the study. They were assessed at rest and after using 10 cmH2O EPAP at random. The variables studied were: oxygen saturation, heart rate and respiratory rate, mean artery pressures and pulmonary artery mean pressures (MAP and PAMP), central venous pressure (CVP) and pulmonary capillary wedge pressure (PAOP), cardiac output and index, and systemic and pulmonary vascular resistances. Patients were divided into subgroups (with ejection fraction <; 50% or > 50%) and data were compared by t test and ANOVA.
Twenty-eight patients were studied (22 men, aged 68 ± 11 years). Comparing the period of rest versus EPAP, the changes observed were: PAOP (11.9 ± 3.8 to 17.1 ± 4.9 mmHg, p < 0.001), PVC (8.7 ± 4.1 to 10.9 ± 4.3 mmHg, p = 0.014), PAMP (21.5 ± 4.2 to 26.5 ± 5.8 mmHg, p < 0.001), MAP (76 ± 10 for 80 ± 10 mmHg, p = 0.035). The other variables showed no significant differences.
EPAP was well tolerated by patients and the hemodynamic changes found showed an increase in pressure measurements of right and left ventricular filling, as well as mean arterial pressure.
[已更正]呼气末正压通气(EPAP)在心脏手术后使用。然而,其对血流动力学的影响尚未得到明确研究。
通过 Swan-Ganz 监测评估 EPAP 对心脏手术后患者血流动力学的影响。
研究纳入血流动力学稳定且接受 Swan-Ganz 导管监测的第一或第二心脏手术后患者。他们在休息时和随机使用 10 cmH2O EPAP 后进行评估。研究的变量包括:氧饱和度、心率和呼吸频率、平均动脉压和肺动脉平均压(MAP 和 PAMP)、中心静脉压(CVP)和肺毛细血管楔压(PAOP)、心输出量和指数以及体循环和肺循环阻力。患者被分为亚组(射血分数 < 50%或 > 50%),并通过 t 检验和 ANOVA 进行数据比较。
研究共纳入 28 例患者(22 名男性,年龄 68 ± 11 岁)。与休息期相比,EPAP 期间观察到的变化包括:PAOP(从 11.9 ± 3.8 至 17.1 ± 4.9 mmHg,p < 0.001)、CVP(从 8.7 ± 4.1 至 10.9 ± 4.3 mmHg,p = 0.014)、PAMP(从 21.5 ± 4.2 至 26.5 ± 5.8 mmHg,p < 0.001)和 MAP(从 76 ± 10 至 80 ± 10 mmHg,p = 0.035)。其他变量无显著差异。
EPAP 被患者耐受良好,所发现的血流动力学变化表明右心室和左心室充盈压以及平均动脉压升高。